T he occurrence of congenital malformations continues to be the leading cause of mortality and serious morbidity in infants of mothers with type 1 and type 2 diabetes in spite of advancement in understanding pregnancy metabolism and treatment. The perinatal morbidity also remains relatively high in women who develop glucose intolerance of any degree with onset or first recognition during pregna...

Alexandra C. Miller et al., Preconceptional Paternal Exposure to Depleted Uranium: Transmission of Genetic Damage to Offspring, Health Physics 99(3), 371-379, 2010 (September) Male transgenic mice with embedded DU pellets were exposed to low (2 DU pellets), medium (4 DU pellets) and high (6 DU pellets) doses of DU over a period of 7 months. They were mated to nontransgenic female mice at 7 mont...

Macrosomia, defined as birth weight > 4 kg, increased in Flanders from 7.3% (4899/67143) in 1991 to 8.63% (6034/69924) in 2010 (p < 0.0001) in singleton pregnancies at term. There are at least 3 important factors contributing to this evolution. (1) Increase of maternal stature and length: during the last century, mean length of Belgian women increased with approximately 10cm to the current valu...

PURPOSE REtard de Croissance Intra-uterin et PALudisme (RECIPAL) is an original preconceptional cohort designed to assess the consequences of malaria during the first trimester of pregnancy, which is a poorly investigated period in Africa and during which malaria may be detrimental to the fetus. PARTICIPANTS For this purpose, a total of 1214 women of reproductive age living in Sô-Ava and Akas...

In 1978, a new era has started in the treatment of infertility by the birth of the first baby from a pregnancy achieved by in-vitro fertilization. Following this, healthy pregnancies have been achieved by assisted reproductive techniques such as in-vitro fertilization by an important percentage of the childless couples. Despite all developments in assisted reproductive techniques, pregnancy rat...

BACKGROUND Despite great strides in improving prenatal care utilization among American women, key perinatal indicators have remained stagnant or worsened in the past decade, and the United States continues to rank near the bottom compared to other developed countries. A new approach is needed if we are to achieve improvements in perinatal health. METHODS To propose a new framework that integr...