Methylisothiazolinone (MI) is a biocidal preservative (1) that is commonly used in cosmetics, wet-wipes, paint, and household products. MI is used in cosmetics (now supported only for rinse-off products) in combination with methylchloroisothiazolinone (MCI) at a concentration of 3.75 ppm. Since 2005, MI has additionally been permitted as a stand-alone preservative in cosmetic products at up to ...

The aim of any packaging system for fresh muscle foods is to prevent or delay undesirable changes to the appearance, flavour, odour, and texture. Deterioration in these qualities can result in economic losses due to consumer rejection of the product. Therefore, a preservative packaging should ideally inhibit undesirable enzyme activities, but not interfere with, or inhibit, activities that are ...

We examined the effects of time, temperature, and a preservative (sodium fluoride) on ethanol concentrations in stored samples of whole blood from living human subjects. We measured the ethanol in the first, second, seventh, and 14th day of storage, by gas chromatography. Samples were stored at 0-3 degrees C and at 22-29 degrees C, with and without preservative. None of these showed significant...

Topical glaucoma therapy is a long termed, usually lifelong. Antiglaucomatous drugs have toxic effects on ocular surface, due to preservative toxicitiy or the drug itself. Adding a lubricant eyedrops to antiglaucomatous therapy, especially if considering the preservative used, can have protective effect. The purpose of this study was to evaluate the stabilty of precorneal tear film in glaucoma ...

This report reviews current literature regarding the association of the pharmaceutical preservative thimerosal and other mercury exposures with the risk for autism. The evidence presented here does not support a causal association between autism and mercury exposure from the preservative thimerosal. The risk for autism from other mercury exposures such as from dental amalgam restorations or env...

Parabens, methyl, ethyl, propyl, benzyl, and butyl, are the most common preservatives in use today. They are the alkyl esters of p-hydroxybenzoic acid and are used extensively because they are relatively nonirritating and nontoxic and offer good antimicrobial coverage. Testing for paraben allergen can be done by patch testing. Two cases of allergic contact dermatitis (ACD) to parabens are used ...

DESCRIPTION YF-VAX®, Yellow Fever Vaccine, for subcutaneous use, is prepared by culturing the 17D-204 strain of yellow fever virus in living avian leukosis virus-free (ALV-free) chicken embryos. The vaccine contains sorbitol and gelatin as a stabilizer, is lyophilized, and is hermetically sealed under nitrogen. No preservative is added. The vaccine must be reconstituted immediately before use w...