Vinyl chloride (VCM) is unloaded from railroad tank cars or tank trucks into pressurized storage spheres. VCM, emulsifiers, and catalysts are metered into polymerization vessels wherein PVC is produced through a chemical reaction in an aqueous medium under controlled conditions of temperature and pressure. After the reaction reaches a predetermined completion, the contents are transferred to a ...

Semi-static dissolution tests using pressurized water reactor spent fuel rod segments and NNWSI reference J-13 well water 1n sealed stainless steel vessels at 85*C are being conducted In support of the Waste Package Task of the NNWSI Project. Test specimens include: bare fuel plus the empty cladding hulls, fuel rod segments with artificially induced cladding defects and water-tight end caps, an...

We developed an organoid culture technique to study the mechanisms involved in arterial remodeling. Resistance arteries were isolated from rat cremaster muscle and mounted in a pressure myograph at 75 mmHg. Vessels were studied during a 4-day culture period in DMEM with either 2% albumin, 10% heat-inactivated FCS (HI-FCS) or 10% dialyzed HI-FCS (12 kDa cut off) added to the perfusate. The album...

Mutations in the coding sequence of the X-linked gene MeCP2 (Methyl CpG-binding protein) are present in around 80% of patients with Rett Syndrome, a common cause of intellectual disability in female and to date without any effective pharmacological treatment. A relevant, and so far unexplored feature of RTT patients, is a marked reduction in peripheral circulation. To investigate the relationsh...

In advanced energy process technologies, like the advanced pressurized circulating fluidized bed (CFB) process conceptualized by Foster Wheeler Corp., there exists a need to transport and control the flow of solids from a high pressure vessel to a low pressure vessel. Solids transport has long been done in the refinery industry and in the CFB combustor industry, but always from a low pressure v...

We tested the hypothesis that endothelin acting through the endothelial ET(B) receptor subtype and the nitric oxide (NO) pathway accounts for reduced myogenic reactivity of the renal resistance vasculature during pregnancy. Small renal arteries (100-200 microm) were isolated from virgin and midterm pregnant rats when gestational renal hyperfiltration and vasodilation are maximal in this species...

An alternating method, in conjunction with the finite element method and a newly developed analytical solution for an elliptical crack in an infinite solid, is used to determine stress intensity factors for semi-elliptical surface flaws in cylindrical pressure vessels. The present finite element alternating method leads to a very inexpensive procedure for routine evaluation of accurate stress i...

The conduction of vasodilation along resistance vessels has been presumed to reflect the electrotonic spread of hyperpolarization from cell to cell along the vessel wall through gap junction channels. However, the vasomotor response to acetylcholine (ACh) encompasses greater distances than can be explained by passive decay. To investigate the underlying mechanism for this behavior, we tested th...

OBJECTIVE Despite the role that extracellular matrix (ECM) plays in vascular signaling, little is known of the complex structural arrangement between specific ECM proteins and vascular smooth muscle cells. Our objective was to examine the hypothesis that adventitial elastin fibers are dominant in vessels subject to longitudinal stretch. METHODS AND RESULTS Cremaster muscle arterioles were iso...

Kozma, Fruzsina, Robert A. Johnson, Fan Zhang, Changhua Yu, Xianglan Tong, and Alberto Nasjletti. Contribution of endogenous carbon monoxide to regulation of diameter in resistance vessels. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1087–R1094, 1999.— Endogenous carbon monoxide was proposed to subserve vasodepressor functions. If so, inhibition of heme oxygenase may be exp...