Objectives: To study cervical colonization in women with premature rupture of membranes and the influence of infection on preterm newborns. Methods: Prospective analysis. Results: 167 (38.66%) from 432 preterm deliveries were complicated with premature prelabour rupture of the membranes (PPROM). Organisms which induce chorioamnionitis and newborns infections mostly belong to group B streptococc...

PROBLEM Bacteria activates Toll-like receptor 4 on immune system cells leading to preterm birth (PTB). The aim of study was to evaluate the impact of maternal and fetal carriage of TLR4 gene polymorphisms on the risk of PTB. METHOD OF STUDY Frequency of TLR4 (896A>G, 1196C>T) variants was determined in 121 women who delivered preterm, 152 women who delivered at term, 49 term newborns and 35 p...

OBJECTIVE To describe developmental characteristics, morphological aspects and incidence of temporal sharp transients (TST) in normal preterm and term newborns at matched conceptional ages (CA). METHOD Neonatal EEGs from two groups of normal newborns were evaluated in order to identify and characterize TST. Group I (n=40) consisted of newborns from 34 to 40 weeks of gestational age (GA) that ...

OBJECTIVE The objective of this study was to estimate national hospital costs for infant admissions that are associated with preterm birth/low birth weight. METHODS Infant (<1 year) hospital discharge data, including delivery, transfers, and readmissions, were analyzed by using the 2001 Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project. The Nationwide Inpatient Samp...

BACKGROUND AND OBJECTIVES Newborns delivered late-preterm (between 340/7 and 366/7 weeks of gestation) are at increased risk of respiratory distress syndrome (RDS). Polymorphisms within the surfactant protein (SP) A and B gene have been shown to predispose to RDS in preterm neonates. The aim of this study was to investigate whether specific SP-A and/or SP-B genetic variants are also associated ...

Late-outgrowth endothelial colony-forming cells (ECFCs), a type of circulating endothelial progenitor cell (EPC), may contribute to pulmonary angiogenesis during development. Cord blood ECFCs from preterm newborns proliferate more rapidly than term ECFCs but are more susceptible to the adverse effects of hyperoxia. Recent studies suggest that bone marrow-derived EPCs protect against experimenta...

The purpose of this study was to determine acceptability of the nucleated red blood cells counts (NRBC) as early prognostic parameter for adverse outcome in preterm neonates born from pregnancies complicated with severe preeclampsia. We analysed 77 premature newborns who were born from pregnancies with severe preeclampsia during eight years (2004-2011) in our tertiary center. Women with other p...

To compare differences in metabolites between newborns with intrauterine growth restriction (IUGR) and those who are appropriate for gestational age (AGA) in order to understand the changes in metabolites of newborns with IUGR and to explore the possible metabolic mechanism of tissue and organ damages in patients with IUGR, with the ultimate goal of providing the basis for clinical intervention...

Introduction: Hyaline Membrane Disease (HMD) remains a major cause of neonatal death and morbidity in infants less than 37 weeks gestation. HMD is an important RDS newborns. To evaluate whether the Gastric Aspirate Shake Test Preterm babies can predict likelihood Disease. Methods: The for prediction was evaluated 81 preterm newborns at NICU Nursery, Patan Hospital. Over 0.5 ml gastric aspirate ...

BACKGROUND: A life-threatening organ dysfunction is a strong predictor of in-hospital mortality and adverse outcomes in pediatric patients full-term neonates. Predictors multiple-organ failure preterm newborns have not yet been sufficiently determined.&#x0D; AIM: To compare the discriminatory ability neonatal sequential (nSOFA) NEOMOD scales as predictors poor very newborns.&#x0D; MATERIALS AND...