Secondary amyloidosis can complicate chronic inflammatory autoimmune diseases. However, the clinical findings of primary amyloidosis may mimic those of primary rheumatologic disorders. We present the case of a 53-year-old woman who presented with dystrophic nail changes, dry eyes, bilateral carpal tunnel syndrome, Raynaud's phenomenon, and high titer positive nucleolar pattern antinuclear antib...

Hepatic involvement in primary amyloidosis (AL type) is not rare but is often clinically silent. However, presentation with jaundice in AL-type amyloidosis is rare, with an incidence of less than 5% reported in the literature. It is considered to be a preterminal sign. We herein report on a case of primary hepatic amyloidosis presenting with severe intrahepatic cholestasis. Viral, drug, alcohol...

Amyloidosis is a pathological process characterised by extracellular deposition of fibrillar protein. Systemic amyloidosis with multiple organ involvement is more common than localised amyloidosis. Localised amyloid deposition in the urinary tract is uncommon and isolated involvement of the ureter and renal pelvis is a rare presentation of this uncommon disease. Primary localised amyloidosis of...

Cardiac involvement occurs frequently in primary amyloidosis and is associated with heart failure hospitalizations and poor survival. The initial presentation of the disease may be misleading, resulting in under-diagnosis of cardiac amyloidosis and late initiation of treatment. We present a case of cardiac amyloidosis initially misdiagnosed as hypertrophic cardiomyopathy and we discuss the key ...

Amyloidosis is a disease characterized by extracellular deposition of fibrillar protein in organs and tissues. Primary tracheal amyloidosis is rare. We report here a case of a 55-year-old man with tracheal amyloidosis hospitalized for acute respiratory insufficiency and with a history of recent episodes of pneumonia. Chest X-ray and chest computed tomography showed tracheal obstruction due to a...

Primary systemic amyloidosis is a rare entity. We report a case of primary systemic amyloidosis without any associated hematological abnormality who presented with macroglossia and hemorrhagic lesions around eyes and sub mammary region. There were soft lobulated masses around perianal region, labia majora and on external auditory meatus obstructing auditory canal. She was also operated for carp...

, Pr. Harrold: This man was 68 when he died. He was a gentlemen's outfitter. Before illness he had had two hernia repairs, and during the 1914-1918 war he had had afew injuries to the arms and legs. He had also had a brief episode of jaundice. His final illness began in the summer of 1962. He died in the summer of 1963. In J962 he noticed the onset of progressive mild exertional dyspnoea. In No...