Glycosaminoglycans are polysaccharides of the extracellular matrix supporting skin wound closure. Mesoglycan is a mixture of glycosaminoglycans such as chondroitin-, dermatan-, heparan-sulfate and heparin and is the main component of Prisma® Skin, a pharmaceutical device developed by Mediolanum Farmaceutici S.p.a. Here, we show the in vitro effects of this device in the new vessels formation by...

Systematic reviews have become very popular. A recent estimate suggests that 22 new systematic reviews are published daily [1]. One reason for this interest is that they serve many purposes. For example, the influential Institute of Medicine has indicated that a systematic review is an essential component when developing clinical practice guidelines within the USA [2]. Some granting agencies ar...

Retention of sealant material is the main determinant for the caries preventive e€ect of sealants. This may partly explain the low interest in using ®ssure sealants in young children, where sucient moisture control may be dicult to obtain. Consequently, almost no data are available in the literature on the e€ect of ®ssure sealants in young pre-school children. The purpose of the present commu...

BACKGROUND Over the last decade there have been a number of guidelines published, aimed at improving the quality of reporting in published studies and reviews. In systematic reviews this may be measured by their compliance with the PRISMA statement. This review aims to evaluate the quality of reporting in published meta-analyses of diagnostic tests, using the PRISMA statement and establish whet...

Resumen. El desarrollo de sistemas software actuales es necesario abordarlo mediante plataformas que permitan describir modelos de arquitectura complejos, distribuidos, evolutivos y reutilizables. PRISMA es un modelo arquitectónico basado en aspectos y componentes que utiliza un lenguaje de definición de componentes (componentes, conectores y sistemas) para definir los elementos de la arquitect...

BACKGROUND Evidence suggests that newborn and child health systematic reviews and meta-analyses exhibit poor quality in reporting. The "Preferred Reporting Items in Systematic Review and Meta-Analysis" (PRISMA) and PRISMA-Protocols (PRISMA-P) checklists have been developed to improve the reporting of systematic review results and protocols, respectively. We aimed to evaluate the clarity and tra...