background heart failure is a major cause of death in thalassemia. the study aimed to determine the diagnostic value of n terminal pro b type natriuretic peptide (nt-pro bnp), to early diagnose the cardiac involvement in beta- thalassemia major patients. materials and methods  80 thalassemia patients aged 7 to 18 years old (patients group), and 80 healthy age and gender matched controls were en...

Let p be an odd prime number, k an imaginary abelian field containing a primitive p-th root of unity, and k∞/k the cyclotomic Zp-extension. Denote by L/k∞ the maximal unramified pro–p abelian extension, and by L′ the maximal intermediate field of L/k∞ in which all prime divisors of k∞ over p split completely. Let N/k∞ (resp. N ′/k∞) be the pro–p abelian extension generated by all p-power roots ...

BACKGROUND Pharyngitis is an inflammatory condition of the pharynx and associated structures commonly caused by the Group A streptococci (GAS). There is a growing interest in discovering plant-based anti-inflammatory compounds as potential alternatives to conventional drugs. This study evaluated anti-inflammatory activity of phytochemical-rich extracts prepared from 12 herbal plants using human...

Influenza remains one of the major epidemic diseases worldwide, and rapid virus replication and collateral lung tissue damage caused by excessive pro-inflammatory host immune cell responses lead to high mortality rates. Thus, novel therapeutic agents that control influenza A virus (IAV) propagation and attenuate excessive pro-inflammatory responses are needed. Polysaccharide extract from Radix ...

MOTIVATION Accurate prediction of protein stability is important for understanding the molecular underpinnings of diseases and for the design of new proteins. We introduce a novel approach for the prediction of changes in protein stability that arise from a single-site amino acid substitution; the approach uses available data on mutations occurring in the same position and in other positions. O...

A fast neutron-mutagenized population of Arabidopsis (Arabidopsis thaliana) Columbia-0 wild-type plants was screened for floral phenotypes and a novel mutant, termed hawaiian skirt (hws), was identified that failed to shed its reproductive organs. The mutation is the consequence of a 28 bp deletion that introduces a premature amber termination codon into the open reading frame of a putative F-b...

BACKGROUND AND OBJECTIVES Sinomenine is an alkaloid compound and a prominent anti-inflammatory agent found in the root of the climbing plant Sinomenium acutum. However, its effects on the mechanism of human mast cell line (HMC)-1-mediated inflammation remained unknown. MATERIALS AND METHODS To provide insight into the biological effects of sinomenine, we examined its influence on the pro-infl...

conclusions there was no significant statistical difference between mta and cem cement in sealing ability (p > 0.05). results the mean apical penetration of dye in the mta group was 0.94 mm while in the cem cement group this was 1.17 mm. eighty percent of the mta group and 75% of the cem cement group didn’t have any dye leakage. the p level was greater than 0.05 (0.592). materials and methods e...

The term “probiotic” is used and misused to identify a growing number of nutritional supplements for horses. In order to understand the varying claims and uses of probiotics, it is critical to define the term as succinctly as possible. To begin, we divide the word into its prefix and root word. The prefix “pro” is a descriptor meaning “supporting or being in favor of,” while “biotic” relates to...