OBJECTIVE To determine reduction in dose of tramadol and side effects in posthysterectomy patients on addition of diclofenac on rectal suppository. STUDY DESIGN Randomized double blinded placebo controlled study. PLACE AND DURATION OF STUDY The Aga Khan University Hospital, Karachi, Pakistan, from August 2004 to January 2006. METHODOLOGY Seventy ASA I and II females, aged 20 and above, wh...

AIMS Miconazole is a synthetic imidazole antifungal that has a broad spectrum of activity against Candida albicans and non-albicans Candida species. The aim of this study was to evaluate the efficacy and safety of miconazole nitrate vaginal suppository and oral fluconazole in treating severe vulvovaginal candidiasis (SVVC). METHODS In this prospective, randomized case control study, 577 cases...

Aim: We assessed the safety and efficacy of three different local anesthesia methods (pudendal nerve blockade, tenoxicam suppository and rectal lidocaine gel) before transrectal ultrasound (TRUS)-guided biopsy of the prostate in this study. Materials and Methods: In our prospective and controlled study, 136 consecutive patients were randomized into four groups: men in group 1 (n=41) received no...

Purpose: Prolong labour contributes to increased perinatal and maternal morbidity. Inhibitory impulses in the form of spasm often impair the dilatation of cervix and prolong the duration of labour. This study was undertaken to compare the effect of intramuscular Valathemate bromide [Epidosin] and Hyoscine N Butylbromide [Buscopan] rectal suppository on duration of labour and rate of cervical di...

Suppository diclofenac instead of intravenous meperidine for postoperative management

background: post episiotomy pain affects a large number of women after the delivery. the common method for pain relief is using oral non-steroidal anti-inflammatory drugs. considering the side effects of these medicines, the aim of present study was to compare the effects of indomethacin suppository and mefenamic acid capsule on post episiotomy pain. methods: in a clinical trial study, sixty wo...

BACKGROUND: We present a case of primary infertility related to extreme cervical stenosis, a subset of cervical factor infertility which accounts for approximately 5% of all clinical infertility referrals. CASE PRESENTATION: A 37 year-old nulligravida was successfully treated with ovulation induction via recombinant follicle stimulating hormone (FSH) and direct intraperitoneal insemination (IPI...

BACKGROUND Chest tube removal is a painful procedure. The goal of this study was to evaluate the effect of cold application in combination with Indomethacin suppository on chest tube removal pain in patients undergoing open heart surgery. MATERIALS AND METHODS This single-blind, double-group clinical trial was performed on 66 patients aged 18-68 years with the chest tube in pleural space. The...