نتایج جستجو برای: prognostic biomarkers

تعداد نتایج: 203607  

2017
Seigo Minami Yoshitaka Ogata Shouichi Ihara Suguru Yamamoto Kiyoshi Komuta

Background Various biomarkers have been shown to predict prognosis in various types of cancers. However, these biomarkers have not been studied in advanced small cell lung cancer (SCLC). The modified Glasgow prognostic score (mGPS) is based on serum albumin level and C-reactive protein (CRP). The prognostic nutritional index (PNI) is a combination of serum albumin level and absolute lymphocyte ...

2014
Sakshi Gulati Pierre Martinez Tejal Joshi Nicolai Juul Birkbak Claudio R. Santos Andrew J. Rowan Lisa Pickering Martin Gore James Larkin Zoltan Szallasi Paul A. Bates Charles Swanton Marco Gerlinger

BACKGROUND Candidate biomarkers have been identified for clear cell renal cell carcinoma (ccRCC) patients, but most have not been validated. OBJECTIVE To validate published ccRCC prognostic biomarkers in an independent patient cohort and to assess intratumour heterogeneity (ITH) of the most promising markers to guide biomarker optimisation. DESIGN, SETTING, AND PARTICIPANTS Cancer-specific ...

2014
Garrett M. Dancik Dan Theodorescu

Few prognostic biomarkers are approved for clinical use primarily because their initial performance cannot be repeated in independent datasets. We posited that robust biomarkers could be obtained by identifying deregulated biological processes shared among tumor types having a common etiology. We performed a gene set enrichment analysis in 20 publicly available gene expression datasets comprisi...

Journal: :Nature Reviews Rheumatology 2019

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