Purpose To report on 2-year results of accelerated corneal collagen cross-linking (CXL) in progressive ectasia using the Avedro KXL system. Design Prospective interventional case series. Methods A total 870 patients (1,192 eyes) attending Moorfields Eye Hospital after CXL were included. All undergoing had keratoconus. Corneas with a minimum stromal thickness Results Twelve- and 24-month follow-...

We aimed to compare the effect of accelerated and conventional corneal collagen cross-linking (CXL) on visual, refractive, and topographic parameters in patients with progressive keratoconus. Between December 2014 and February 2016, at Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Iran, we compared 37 eyes of 21 patients treated by conventional CXL (CCXL; 3 mW/cm2 in...

We report a case of pharmacologic regression of Urrets-Zavalia syndrome, following deep lamellar keratoplasty for severe keratoconus. Sympatholytic and parasympathomimetic drops were administered and a progressive reduction of mydriasis and restoring of pupillary kinetics were observed. Four years after surgery, it was resulting in only slight residual anisocoria.

Introduction In a broad review, evidence that the corneal biomechanical properties influence the results and outcomes of various ocular measurements and procedures has existed for some time [1,2]. However, assessing the biomechanical properties of corneal tissue in vivo has previously not been possible. With the recent introduction of the Reichert Ocular Response Analyzer (ORA), direct clinical...

Keratoconus is an eye disease characterized by a slow progressive thinning and cone shaped protrusion of the central region of the cornea. rcsulting in loss of vision due t o irregular astigmastism and scarring [ I ] . I t usually begins in the early teens, is more prevalent in women, and most estimates of its frequency are within the range 4-230 per 100000 individuals 121. At the present time ...

The purpose of this retrospective study was to report the results of iontophoretic corneal collagen crosslinking (I-CXL) with riboflavin and ultraviolet A irradiation in patients affected by keratoconus, each with thinnest pachymetry values of <400 μ (with epithelium) and not treatable using standard epithelium-off technique.Fifteen eyes of 15 patients affected by progressive keratoconus and wi...

The cornea is one of the principal refractive elements in the human eye and plays a crucial role in the process of vision. Keratoconus is the most common corneal dystrophy, found mostly among young adults. It is characterized by a reduced number of collagen cross-links in the corneal stroma, resulting in reduced biomechanical stability and an abnormal shape of the cornea. These changes lead to ...

To assess risk factors for progression following corneal collagen crosslinking (CXL) in eyes with keratoconus. Charts of patients who developed conventional CXL treatment (Dresden protocol) were retrospectively evaluated two centers (Center 1 and Center 2). 871 a total 676 analyzed. Progression was defined as > diopter (D) increase maximum keratometry (Kmax) readings compared to baseline. noted...

Keratoconus is a progressive, non-inflammatory corneal ectasia characterized by thinning and weakening of the corneal stroma which results in its' protrusion. The onset is during puberty and progresses until the fourth decade of life. In earlier stages, good visual acuity can be provided with spectacles. With progression, contact lenses are considered to be a better therapy. Aim of this study w...