نتایج جستجو برای: pronephros
تعداد نتایج: 272 فیلتر نتایج به سال:
Edematous frog larvm are among the commonest types of abnormalities which can be produced by experimental means. When ova of the twoor four-celled stage are placed in solutions of potassium cyanide, acetone, butyric acid, or ethyl alcohol for from 12 to 24 hours, and then subsequently developed in t ap water, an edema, tous condition of the body frequently, though not always, results. Hertwig 1...
Polycystic kidney disease (PKD) is a common hereditary disease in humans. Recent studies have shown an increasing number of ciliary genes that are involved in the pathogenesis of PKD. In this study, the Gli-similar3 (glis3) gene was identified as the causal gene of the medaka pc mutant, a model of PKD. In the pc mutant, a transposon was found to be inserted into the fourth intron of the pc/glis...
The transcription factor HNF1B, encoded by the TCF2 gene, plays an important role in the organogenesis of vertebrates. In humans, heterozygous mutations of HNF1B are associated with several diseases, such as pancreatic β-cell dysfunction leading to maturity-onset diabetes of the young (MODY5), defective kidney development, disturbed liver function, pancreas atrophy, and malformations of the gen...
Elucidating the gene regulatory networks that control kidney development can provide information about the origins of renal birth defects and kidney disease, as well as insights relevant to the design of clinical interventions for these conditions. The kidney is composed of functional units termed nephrons. Renal malfunction often arises from damage to cells known as podocytes, which are highly...
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