Objective: HIV-1 has been a killer disease since two decades ago, while a potential cure has not yet discovered due to the fast mutations of the HIV1 enzymes,i.e reverse transcriptase, integrase, and protease. Apart of HIV-1, malaria has been the biggest cause of death in human and it is mostly found in the East part of Indonesia. There are some enzymes in the food vacuole of Plasmodium falcipa...

This study aims to produce a mix of enzymes through Solid State Fermentation (SSF) raw materials. Four different, easily available, agro-industrial wastes were evaluated as SSF substrates for production by Cryphonectria parasitica (Murr.) Barr. environmental strains named CpA, CpB2, CpC4, and CpC7. Among the tested wastes, organic wheat bran human use animal feed better supports C. growth prote...

In the present study, forty-five bacterial isolates were obtained from previously unstudied soil samples in Bal?kl?göl, ?anl?urfa. Based on their enzim production capacities, six designated as BGL-22, BGL-26, BGL-27, BGL-37, BGL-38 and BGL-39 selected for further studies. Conventional molecular identification results showed that bacteria belonged to Bacillus genus. Among these strains, highest ...

Compost is a highly humified organic fertilizer, rich in nutrients and source of variety aerobic microorganisms, including actinomycetes, which develop response to different levels temperature, humidity, oxygen pH. Microbes growing on the compost are believed have ability produce extracellular hydrolytic enzymes. The purpose this study was determine thermophilic actinomycetes XM21 isolated from...

High Potency Protease is a concentrated source of protease enzymes, which have been shown to improve protein digestion, reduce inflammation and speed the healing of wounds, inhibit the formation of blood clots, protect against intestinal parasitic infection and the overgrowth of yeast, and support immune function. High Potency Protease also contains bentonite, a concentrated source of minerals ...

Alkaline proteases are the most important groups of commercial enzymes, which have been broadly used in industrial processes. In this study, Bacillus sp. PTCC 1538 was selected as a biological agent to produce alkaline protease. Enzyme production under submerge fermentation using waste effluent investigated. Since costs raw material plays an role cost enzyme production, corn steep liquor (CSL) ...

Protease inhibitors, which can inhibit insect digestive enzymes, and carbohydrate binding lectins are potential control mechanisms against herbivorous insects. Larval midgut extracts fi-om Eldana saccharina Walker (Lepidoptera: Pyralidae) were assayed for protease activity in the presence of protease inhibitors in order to determine the dominant protease types (serine, aspartic, metalloor cyste...

This paper describes the immobilization of the neutral protease from Bacillus subtilis and its application in the regioselective hydrolysis of acetylated nucleosides, including building blocks useful for the preparation of anticancer products. Regarding the immobilization study, different results have been obtained depending on the immobilization procedure. Epoxy hydrophobic carriers gave a poo...

Removal of ubiquitin from modified proteins is an important process to regulate the ubiquitin system. Roughly 100 dedicated enzymes for this purpose, the deubiquitinases, exist in human cells and are intricately involved in a wide variety of cellular processes, although many enzymes remain unstudied to date. The deubiquitinases consist of five enzyme families that contain USP, OTU, UCH, Josephi...