reactive oxygen species (ros)plays an important role in sperm motility. the physiological generation at low concentration induces beneficial effects on sperm functions and plays a significant role in sperm metabolism. meanwhile, the excessive generation of reactive oxygen species can overwhelm protective mechanism and triggers changes in lipid and protein layers of sperm plasma membrane, which ...

Esophageal squamous cell carcinoma (ESCC) is the most prevalent malignant gastrointestinal tumor. Ion channels contribute to tumor growth and progression through interactions with their neighboring molecules including lipids. The dysregulation of membrane ion lipid metabolism may epithelial–mesenchymal transition (EMT), leading metastatic progression. Herein, transcriptome profiles patients ESC...

a total of 1440 arian chicks were used in this study to determine the effects of diet formulation methods on performance and blood parameters of arian chicks. eight diets were arranged in a 2×2×2 factorial design with 2 methods of energy expression (apparent (amen) and true (tmen) metabolizable energy corrected to n equilibrium), 2 methods of amino acids content of feeds (total (taaf) and diges...

Protein–metabolite interactions play an important role in the cell’s metabolism and many methods have been developed to screen them vitro . However, few can be applied at a large scale not alter biological state. Here we describe proteometabolomic approach, using chromatography generate cell fractions which are then analyzed with mass spectrometry for both protein metabolite identification. Int...

alzheimer’s disease (ad) is the most common cause of dementia caused by complicated interactions between genetic and environmental factors. molecular genetic research has provided valuable information regarding the genetic etiology of the disease. identifying the genetics of ad not only could shed light on disease pathogenesis, but it may also provide potential targets for effective treatment, ...