Withania somnifera Dunal (Ashwangdha), a popular medicinal herb of Ayurveda is used for health, vitality, longevity and rejuvenation properties. It is a common ingredient of polyherbal or herbomineral formulations and used for preventive or therapeutic polypharmaceutical use. Present article emphasized on the studies, which provides the pharmacological basis of its use in cardiovascular disease...

Hypocholesteremic and antioxidant effects of Withania somnifera (WS) Dunal (Solanaceae) were investigated in hypercholesteremic male albino rats. When the root powder of WS was added to the diet at 0.75 and 1.5 gm/rat/day, hypercholesteremic animals registered significant decreases in total lipids (-40.54%; -50.69%), cholesterol (-41.58%; -53.01%) and triglycerides (-31.25%; - 44.85%) in plasma...

The effect of an Ayurvedic preparation consisting of Swasakutara, Curcuma longa (Haridra) and Withania somnifera (Asvagandha) is accessed in 12 patients of tropical eosinphilia. The modern control drug Hetrazan is used in another batch of 11 patients for comparison. The Ayurvedic compound causes complete relief of most of the clinical signs and symptoms associated with the disease and reduces E...

Withania somnifera (L.) Dunal., commonly referred to as Ashwagandha, is a medicinal plant from the solanaceae family with wide range of pharmacological properties. W. rich source withanolides, such withanolide A, B, D, withaferin etc. and these molecules are attributed for large number activities. In present study, impact heavy metals cadmium (Cd), mercury (Hg), lead (Pb) has been assessed on g...

Sleep deprivation disrupts significantly sleep pattern and cause poor quality of sleep. The aim the present study was to explore role of Withania somniferra root extract in sleep-disturbed rats. Male wistar rats (n=5-6/group) were sleep deprived for 24 h using grid suspended over water method. Withania somniferra extract (100 mg/kg) was administered intraperitoneally (i.p.) 30 min before actual...

Clinical efficacy and safety of a herbomineral drug containing withania somnifera Asparagus racemosus glycyrrhiza glabra, mucuna pruriens, Myristica fragrans, Anauchus pyrethrum, Ipomoea digitata, sida cordifolia, zine ash complex and high energy carbohydrate molecules were evaluated in an open study. All patients treated with the drug reported good improvement in the various symptomatology of ...

Purpose The herb Ashwagandha (Withania somnifera, Dunal), has been used for centuries in Ayurveda as rasayana – promoter of longevity, well-being, and disease prevention. Traditional use combines the herb with a carrier substance called “anupana,” believed to help aid in bioavailability and absorption. To compare the effects of Ashwagandha root extract plus anupana on human immune activation to...