In the study of many types of biological material it has become of increasing importance to determine accurately extremely small amounts of iron. Since color reactions are, as a rule, very sensitive, calorimetric procedures are particularly useful in the microanalytical field, and several calorimetric methods have appeared in the literature on iron determination. Although the extremely sensitiv...

In the study of many types of biological material it has become of increasing importance to determine accurately extremely small amounts of iron. Since color reactions are, as a rule, very sensitive, calorimetric procedures are particularly useful in the microanalytical field, and several calorimetric methods have appeared in the literature on iron determination. Although the extremely sensitiv...

Aim This study is to determine seven phenolic constituents (salvianolic acid A, salvianolic acid B, rosmarinic acid, caffeic acid, protocatechuic aldehyde, protocatechuic acid, danshensu) of isolated from Radix Salvia miltiorrhizae in rat plasma and to study the pharmacokinetics of the seven phenolic constituents. Methods A rapid and sensitive method for the determination of seven phenolic cons...

BACKGROUND AND PURPOSE Antibiotic combinations are used to enhance antibacterial efficacy and to prevent the development of resistance. In this study, the in vitro activities of antibiotic and phytochemical combinations against Pseudomonas aeruginosa were tested by the fractional inhibitory concentration method, derived from the minimal inhibitory concentrations (MICs) of the agents in combinat...

Oxidative stress is one of the important mechanisms involved in Dexamethasone (Dex)-induced hypertension. Protocatechuic acid (PCA) is a natural compound with high antioxidant capacity. In this investigation, the effect of pretreatment with PCA was studied in Dex-induced hypertensive male Wistar rats. For induction of hypertension, Dex was injected subcutaneously for 14 days. PCA (50, 100 and 2...

In an effort to characterize active principles for diabetic complication from medicinal mushroom, aldose reductase inhibitors were isolated from the fruiting body of Phellinus linteus and identified as hispidin (5), phelligridimer A (6), davallialactone (7), methyldavallialactone (8), hypholomine B (9), interfungins A (10), and inoscavin A (11), together with protocatechuic acid (1), protocatec...

The leukotrienes constitute a group of arachidonic acid-derived compounds with biologic activities suggesting important roles in inflammation and immediate hypersensitivity. Epidermis-type lipoxygenase-3 (ALOXE3), a distinct subclass within the multigene family of mammalian lipoxygenases, is a novel isoenzyme involved in the metabolism of leukotrienes and plays a very important role in skin bar...

Pro-oxidant effects of phenolic compounds are usually correlated to the one-electron redox potential of the phenoxyl radicals. Here we demonstrated that, besides their oxidizability, hydrophobicity can also be a decisive factor. We found that esterification of protocatechuic acid (P0) provoked a profound influence in its pro-oxidant capacity. The esters bearing alkyl chains containing two (P2),...