Chronic obstructive lung disease (COPD) is a chronic multisystem disease with a considerable burden. One of its most common complications is pulmonary artery hypertension (PAH). It has been demonstrated that the development of PAH is correlated with decreased quality of life and survival. Different medications have been proposed for the treatment of PAH, among which one can name statins. Howeve...

Pulmonary hypertension is a progressive disorder which often leads to right ventricular failure and death. While the existing classification system for pulmonary hypertension does not account for the impact of diabetes mellitus, evidence is emerging that suggests that diabetes is associated with pulmonary hypertension and that diabetes modifies the course of pulmonary hypertension. There is als...

Pulmonary hypertension complicating idiopathic pulmonary fibrosis, also known as secondary pulmonary hypertension, represents a major source of morbidity and mortality in affected patients. While the study of primary pulmonary arterial hypertension has yielded several therapies, the same is not true for the treatment of pulmonary hypertension secondary to pulmonary fibrosis. Recent studies have...

It is well-known that pulmonary hypertension can complicate infection by the human immunodeficiency virus (HIV). The incidence of primary pulmonary hypertension in HIV positive patients is unknown, but could be higher than 0.5%, in comparison with an 0.02% incidence in the general population. Since 1987, 131 cases of pulmonary hypertension associated with HIV infection have been published.1 A t...

OBJECTIVE To compare the visualisation of bronchopulmonary collaterals and bronchopulmonary collateral blood flow in patients with chronic thromboembolic pulmonary hypertension 2nd primary pulmonary hypertension. SETTING Referral centre for cardiology at an academic hospital. PATIENTS Nine patients with chronic thromboembolic pulmonary hypertension and 17 with primary pulmonary hypertension...

Two cases of 'primary' pulmonary hypertension with hypereosinophilia, in whom adult filarial worms were found, are described from Ceylon. The significance of the association between filariasis, tropical pulmonary eosinophilia, and pulmonary hypertension is discussed. It is postulated that pulmonary hypertension followed the chronic destruction of microfilariae in the lungs and their embolizatio...

Pulmonary artery pressure elevation complicates the course of many complex disorders treated in a noncardiac intensive care unit. Acute pulmonary hypertension, however, remains underdiagnosed and its treatment frequently begins only after serious complications have developed. Significant pathophysiologic differences between acute and chronic pulmonary hypertension make current classification an...