This article addresses neutrophilic dermatoses, thus complementing the previous article (part I). The following dermatoses are introduced and discussed: subcorneal pustular dermatosis (Sneddon-Wilkinson disease), dermatitis cruris pustulosa et atrophicans, acute generalized exanthematous pustulosis, continuous Hallopeau acrodermatitis, palmoplantar pustulosis, infantile acropustulosis, Andrews'...

Acute generalized exanthematous pustulosis (AGEP), a member of the “neutrophilic dermatoses” was first described by Baker and Ryan in 1968 as exanthematic pustular psoriasis (Baker & Ryan 1968). According to the European Study of Serious Cutaneous Adverse Reactions (EuroSCAR), the incidence ranges from 1 to 5 cases per million per year and the mortality rate approaches 1% to 2%, with the equal ...

Introduction Generalized pustular psoriasis (GPP) is a rare, potentially life-threatening disease characterised by recurrent flares of widespread neutrophilic aseptic skin eruption. Despite the availability approved biologics for GPP in Japan, Taiwan and Thailand, associated evidence largely based on uncontrolled studies which acute were not directly assessed. Therefore, there high unmet need t...

Generalized pustular psoriasis, or psoriasis of von Zumbusch, is an acute and severe clinical form of psoriasis, which usually occurs in patients with psoriasis undergoing aggravating factors. In this work, we report the case of a female patient, 70 years old, who developed generalized pustular psoriasis symptoms while reducing the dose of oral corticosteroids, improperly introduced for the tre...

IgA pemphigus is a newly characterized group of autoimmune intraepidermal blistering diseases presenting as vesiculopustular eruptions with a predilection in axillary and groin areas. Immunopathologically, IgA deposition in the intercellular space of the epidermis is present in all cases of IgA pemphigus by direct immunofluorescence. However, unlike pemphigus vulgaris, IgA pemphigus carries a r...

Infliximab is genetically produced murine chimeric antibody (from the Greek mythological monstrous fire-breathing hybrid chimera composed of parts of more than one animal) that contains polypeptides from different species, such as humans, in order to reduce antibody’s immunogenicity. It consists of 25% murine sequences in the variable region of antibody, but some patients have developed antichi...

background and aims. predicting the teeth eruption time is a valuable tool in pediatric dentistry since it can affects scheduling dental and orthodontic treatments. this study investigated the relationship between the eruption time of first primary and permanent teeth and the variation in the eruption time considering socioeconomic status (ses) in a 9-year population- based cohort study. materi...

BACKGROUND Pustular psoriasis is an uncommon psoriasis variant, clinically characterized as small sterile pustules on an erythematous base. Evidence for therapy is lacking, and many currently employed systemic therapeutics carry risks of significant side effects, without specifically targeting disease etiology which includes the aggregation of neutrophils. OBSERVATIONS We report therapy with ...

Two multigravidae aged 27 and 29 years, with previous uneventful pregnancies, second being psoriatic, reported at 24 and 28 weeks of pregnancies, with generalized pustular lesions. Laboratory findings, including serum calcium were normal. Ultrasonography showed normal fetal growth. Histopathology confirmed pustular psoriasis. Patients were put on cyclosporine 3 mg/ kg weight/ day after failure ...

EPDS: erosive pustular dermatosis of the scalp INTRODUCTION Erosive pustular dermatosis of the scalp (EPDS) is an uncommon condition that is reported after local injuries including burns, cryotherapy, radiation therapy, photodynamic therapy, skin grafts, and hair transplantation as well as topical medication treatments including retinoids, imiquimod, and 5fluorouracil. We present a case of eros...