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Oxidative stress plays various roles in the development and progression of IgA nephropathy, while bilirubin is known as a potent antioxidant. We therefore hypothesized that serum bilirubin would be associated with renal prognosis in IgA nephropathy. The study subjects comprised 1,458 adult patients with primary IgA nephropathy in Korea. We grouped patients according to the following quartile le...
Experimental and epidemiologic data support a protective role for melatonin in breast cancer etiology, yet studies in premenopausal women are scarce. In a case-control study nested within the Nurses' Health Study II cohort, we measured the concentration of melatonin's major urinary metabolite, 6-sulfatoxymelatonin (aMT6s), in urine samples collected between 1996 and 1999 among 600 breast cancer...
OBJECTIVE The hypothesis of carotenoid having a preventive role in diabetes is suggested by their antioxidant properties. In this report, we investigated the relationship between baseline total plasma carotenoid levels and 9-year onset of dysglycemia (impaired fasting glucose or type 2 diabetes) in a healthy elderly population. RESEARCH DESIGN AND METHODS The Epidemiology of Vascular Ageing S...
We present an experimental study of density and order fluctuations in the vicinity of the solid-liquid-like transition that occurs in a vibrated quasi-two-dimensional granular system. The two-dimensional projected static and dynamic correlation functions are studied. We show that density fluctuations, characterized through the structure factor, increase in size and intensity as the transition i...
Presentation Preference: Oral or Poster Objectives: In the United Kingdom (UK), occupational therapy (OT) is a routine component of care pathways for total hip and knee replacement. Due to the multi-modal nature of ERAS, understanding the relative importance of different component steps is difficult. Therefore, this study sought the patient’s perspective on the importance of OT input within an ...
OBJECTIVE to evaluate primary care drug utilisation during the last year of life, focusing on antidiabetic and cardiovascular drugs, in patients of advanced age with diabetes. DESIGN population-based cohort study. SETTING primary care database in the UK. SUBJECTS patients with type 2 diabetes who died at over 80 years of age between 2011 and 13. METHODS main outcome measures included pr...
BACKGROUND The relationships between uric acid and metabolic syndrome (MetS) and diabetes, as well as the gender differences in these relationships are controversial. METHODS Medical check-up data from 2,449 Japanese men and 1,448 Japanese women were examined. The prevalence of MetS and diabetes was calculated by the quartiles of serum levels of uric acid. Correlation coefficients between uri...
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