INTRODUCTION AND OBJECTIVES Treatment with ferric carboxymaltose improves symptoms, functional capacity, and quality of life in patients with chronic heart failure and iron deficiency. The aim of this study was to assess the cost-effectiveness of ferric carboxymaltose treatment vs no treatment in these patients. METHODS We used an economic model based on the Spanish National Health System, wi...

INTRODUCTION Data on quality of life beyond 2 years after intensive care discharge are limited and we aimed to explore this area further. Our objective was to quantify quality of life and health utilities in the 5 years after intensive care discharge. METHODS A prospective longitudinal cohort study in a University Hospital in the UK. Quality of life was assessed from the period before ICU adm...

OBJECTIVE To study long-term mortality, quality of life (QOL), quality-adjusted life years (QALYs), and costs per QALY in an unselected intensive care unit (ICU) patient population with severe sepsis. DESIGN Prospective observational cohort study. SETTING Twenty-four ICUs in Finland. PATIENTS A total of 470 adult patients with severe sepsis who were treated in ICUs between November 1, 200...

BACKGROUND Quality-adjusted life-years (QALYs) use preference-based measurements of health-related quality-of-life (HRQOL) to provide an assessment of the overall burden of disease using a single number. PURPOSE This study estimated QALYs lost contributed by smoking and obesity for U.S. adults from 1993 to 2008. METHODS Population HRQOL data were from the 1993-2008 Behavioral Risk Factor Su...

BACKGROUND Seasonal affective disorder (SAD) episodes will recur annually without effective intervention. Effectiveness of such interventions is traditionally measured with depression-specific tools (e.g., Beck Depression Inventory 2nd Edition; BDI-II). In a climate of potentially scarce resources, generic outcomes, such as Quality Adjusted Life Years (QALYs), are recommended for cost-effective...

Quality-adjusted life-years (QALYs) are the most common utility measure in medical decision analysis and economic evaluations of health care. This paper presents an axiomatization of QALYs under cumulative prospect theory (CPT), currently the most influential model for decision under uncertainty. Because the set of health states need not be endowed with a natural topology that is connected, we ...