Quantitative Yttrium-90 ((90)Y) bremsstrahlung single photon emission computed tomography (SPECT) imaging has shown great potential to provide reliable estimates of (90)Y activity distribution for targeted radionuclide therapy dosimetry applications. One factor that potentially affects the reliability of the activity estimates is the choice of the acquisition energy window. In contrast to imagi...

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Objectives: The monitoring of cancer treatment response to chemotherapy is considered an essential strategy for follow-up of patients. The aim of this study was to evaluate the use of 99mTc-glucarate as a radiotracer for in vivo quantification and visualization of necrotic area and therapeutic effect of paclitaxel in ovarian cancer xenografted nude mice. Materials and Methods: After implantatio...

The field of medical imaging is undergoing a radical shift, from subjective interpretation to quantitative analysis and measurement. This transformation is well established in the clinical trials arena, and is beginning to enter the diagnostic field as well. This paper will consider the implications of this change in terms of instrumentation, procedure, and analysis. It will include a brief rev...

An ultrasonic transmission technique is described which images the velocity variation within metal parts. The arrival time of the first ultrasonic pulse to traverse the object is detected and displayed as a gray scale on a cathode ray tube while the part is being scannerJ hori:tontally and vertically. The velocity variation imaged within severa 1 cast turbine parts will be shown. ihe system can...

PURPOSE MV-CEA is an oncolytic measles virus currently being tested in patients with ovarian cancer and whose propagation can be monitored by measuring blood carcinoembryonic antigen (CEA) levels. MV-NIS is an oncolytic measles virus coding for the thyroidal sodium iodide symporter (NIS) whose propagation can be mapped by serial radioiodine imaging. Expression of both CEA and NIS genes from a s...