In the present scenario, usage of pesticides are inevitable to meet the demands of growing population and to secure the food grain production, there is need for regular screening of milk and milk products for pesticide residues which is being felt in the trade and also at the consumers level. The present work was undertaken to study the effect of heat processing on degradation of various Organo...

Liquid chromatography (LC) coupled with mass spectrometry (MS) is widely used for the determination of mycotoxins in cereals and cereal-based products. In addition to the regulated mycotoxins, for which official control is required, LC-MS is often used for the screening of a large range of mycotoxins and/or for the identification and characterization of novel metabolites. This review provides i...

The presence of erectile dysfunction (ED) drugs in adulterated dietary supplements, mainly pharmaceutical dosage forms, is frequently addressed the literature. Little attention given to food products despite their increasing adulteration trend. To address this knowledge gap targeted, suspected-target, and non-targeted strategies were utilised analyse ED analogues powdered drink mix (PDM), honey...

An easy, simple and efficient analytical method was standardized and validated for the estimation of residues of propamocarb in tomato and soil. QuEChERS method included extraction of the sample with ethyl acetate and cleanup by treatment with PSA and graphatised carbon. Final clear extracts of ethyl acetate were concentrated under vacuum to almost dryness and reconstituted into hexane. The res...

Kresoxim-methyl is nowadays widely used to combat a diversity of common diseases affecting high-value crops. In this article, we report the development and characterization of two novel immunoassays for the analysis of this pioneer strobilurin fungicide, and for the first time, a validation study with food samples was performed. A direct and an indirect competitive immunoassay based on a new an...

Increasing emissions of chemical compounds to the environment, especially of pesticides, is one of factors that may explain present honeybee colony losses. In this work, an analytical method employing liquid chromatography-tandem mass spectrometry (LC-MS/MS) was optimized for the simultaneous screening of 19 pesticides which have not been yet determined in honeybee samples from northern Poland ...

This application note describes a sensitive and reliable method for the determination of perfluorinated carboxylic acids (PFCAs) in human plasma. PFCAs were extracted from a plasma sample using an optimized QuEChERS protocol, followed by CE-MS/MS analysis. The optimal separation of investigated PFCAs was achieved in less than 9 minutes using 25 mM ammonium acetate buffer and 1 % isopropanol (pH...

For the first time, a multi-residue methodfor simultaneous determination of 41LC-amenable pesticides in rice, belonging to different chemical classes has been developed in Iran by LC-MS/MS. The pesticides were analyzed simultaneously in a single run using positive electrospray ionization with multiple reaction monitoring (MRM) after extraction with slightly modified QuEChERS method. The calibra...

Using capillary electrophoresis combined with tandem mass spectrometry, we have developed a method to simultaneously detect lorazepam, clonazepam, temazepam, oxazepam, diazepam, and nitrazepam in urine. The urine samples were submitted to a modified QuEChERS extraction procedure, followed by electrophoretic separation in 0.1 M formic acid electrolyte (pH 2.4) using a polyvinyl alcohol (PVA)-coa...

Introduction There are many analytical challenges encountered with the extraction and quantification of pesticide residues in difficult sample matrices such as tuber crops, like yam (Dioscorea spp.), taro (Colocasia esculenta) and sweet potato (Ipomoea batatas L.). In our experience, a workflow solution based on extraction using the accelerated solvent extraction technique, followed by determin...