A rapid, high-throughput method employing ultra-performance liquid chromatography with tandem quadrupole mass spectrometry (UPLC-MS/MS) was developed and optimized for simultaneous quantification and confirmation of 64 pesticide residues and their toxic metabolites in fruit extracts prepared by a buffered QuEChERS procedure. The total time required for UPLC-MS/MS analysis was 8 min plus 2 min f...

This application note describes a sensitive and reliable method for determination of 20 polyfluoroalkane substances (PFASs) in milk based on the work published by Yu, et al. previously [1]. The milk sample was initially extracted and cleaned up using an optimized QuEChERS protocol, followed by an online interference trapping LC-MS/MS analysis. Using stable isotope labeled internal standards for...

For the first time, a multi-residue methodfor simultaneous determination of 41LC-amenable pesticides in rice, belonging to different chemical classes has been developed in Iran by LC-MS/MS. The pesticides were analyzed simultaneously in a single run using positive electrospray ionization with multiple reaction monitoring (MRM) after extraction with slightly modified QuEChERS method. The calibra...


 ABSTRACT. Optimized QuEChERS (quick, easy, cheap, effective, rugged and safe) method of sample preparation was employed for five selected pharmaceutical compounds on its advantage simplicity, less extraction solvent time. Different parameters affecting the efficiency target analyte optimized. Since developed pesticides, uses pharmaceuticals need modification evaluation different paramete...

Article history: Received 26 January 2014 Received in revised form 10 March 2014 Accepted 12 March 2014 Available online 5 April 2014

Abstract Purpose Organochlorine pesticides (OCPs) like lindane and DDT have been used extensively after World War II until the 1990s. Still, residues of these can be found in agricultural soils all over world, especially developing countries. Often, they occur extensive areas elevated concentrations so that food safety is jeopardized. Hence, simple, cheap, fast analytical methods are needed for...

A modified QuEChERS method was developed for the simultaneous analysis of tylosin (Tyl) and metronidazole (MNZ) residues in shrimp samples using LC-ESI-MS/MS. The sample extraction procedure based on QuEChERS, cleanup dispersive solid-phase (dSPE). Octadecyl (C18) primary secondary amine (PSA) sorbents were used dSPE cleanup. Analyte chromatographic separations carried out a ZORBAX RRHD Eclipse...