Myocardial perfusion imaging (MPI) is a wellestablished noninvasive method of assessing coronary blood flow.1–5 MPI is capable of identifying regional abnormalities in coronary artery blood flow and determining their physiological relevance to myocardial function and viability. MPI requires the intravenous injection of a radioactive blood flow marker followed by imaging of regional myocardial u...

Current patient release criteria established in NRB-99/2009 relate to four radionuclides used Russia that period of the document preparation. These were calculated only considering radionuclide decay. Thus, these give conservative assessments which require stay dedicated protected room (“hot” room) radiotherapy department for several days and do not allow therapy be given outpatient hospital ce...

TO THE EDITOR: As ethanol is frequently used in radiopharmaceutical injections, we were interested in the effect of ethanol by injection. Several questions crossed our mind. What is the maximum concentration of ethanol that we can inject without side effects? What is the hemolytic potential of ethanol? Can we dilute ethanol-containing injections just with water? Ethanol can be used in radiophar...

BACKGROUND Preliminary studies have shown that (99m)Tc-hexakis-2-methoxyisobutylisonitrile (MIBI) is an interesting tracer for various tumors. The aim of this study was to determine the feasibility of using (99m)Tc-MIBI as a diagnostic and staging procedure for lung cancer. METHODS We prospectively compared the results of biopsy with (99m)Tc-MIBI imaging in patients with potentially resectabl...

Positron emission tomography (PET) is a coalition of physics, chemistry, physiology, and medicine united in an effort to measure physiologic parameters noninvasively. A PET study consists of producing radiotracers, synthesizing radiopharmaceuticals from the tracers, administering the radiopharmaceutical to a patient, measuring the resulting radioactivity distribution in an organ of interest, an...

A Bayesian method is presented for simultaneously segmenting and reconstructing emission computed tomography (ECT) images and for incorporating high-resolution, anatomical information into those reconstructions. The anatomical information is often available from other imaging modalities such as computed tomography (CT) or magnetic resonance imaging (MRI). The Bayesian procedure models the ECT r...

[(11)C]-choline is an effective PET tracer used for imaging of neoplastic lesions and metastases of the prostate cancer. However, its production can be a challenge for manufacturers, as it has not yet been described in Polish or European pharmacopoeia. In this study the technical aspects of [(11)C]-choline production are described and detailed process parameters are provided. The quality contro...

beta-emitting 166Ho (t1/2 = 26.78 hours, E(beta)max = 1.8 MeV) complexed with the phosphonic acid chelator, 1,4,7,10 tetraazacyclododecane-1,4,7,10-tetra(methylene phosphonic acid) (DOTMP) at a ligand-to-metal ratio of 1.5:1 binds to bone. This radioactive complex is a marrow-ablating radiopharmaceutical that appears useful for preparation of bone marrow (BM) transplant recipients without the m...