gastrointestinal (gi) bleeding in pediatric patients has several causes. vascular malformation of the small bowel is a rare disease leading to pediatric gi bleeding. to our knowledge, few reports describe ultrasound and computed tomography findings of venous malformations involving the small bowel. we present a case of long-segmental and circumferential vascular malformation that led to gi blee...

menorrhagia is the most common symptom that is experienced by women with bleeding disorders. von willebrand disease (vwd) is the most common congenital human bleeding disorder that is manifested as a quantitative deficiency in von willebrand factor (vwf) or dysfunction of this factor. the frequency of vwd is similar in both men and women. however, vwd is more readily detected in women due to th...

Introduction. Platelet dense granule disorders are a group of rare heterogeneous the blood coagulation system in which bleeding occurs due to functional and morphological platelet organelles accumulating phosphates bioactive amines. Aim — present clinical case 37-year-old patient with severe hemorrhagic syndrome. Basic information. An observation occurrence manifestations unspecified genesis is...

Massive hemoperitoneum secondary to ruptured corpus luteum is a rare but serious and life-threatening complication for women with congenital bleeding disorders and may lead to surgical interventions and even oophorectomy. Congenital afibrinogenemia is a rare inherited coagulation disorder. As it can be asymptomatic, its clinical manifestations vary from minimal tendency of bleeding to life-thre...

neurofibromatosis type 1, also known as von recklinghausen disease, is an autosomal dominant disorder with an incidence of 1 per 4000. neurofibromas are benign, heterogeneous tumors arising from the connective tissue of peripheral nerve sheaths, especially the endoneurium. visceral involvement in disseminated neurofibromatosis is rare. neurofibroma occurs most frequently in the stomach and jeju...

During the haemostatic response, the formation of a primary platelet plug limits bleeding and provides a surface for clotting factors to assemble and become activated. The initial platelet plug is stabilized by fibrin monomers, covalently cross-linked by FXIII, forming a platelets-fibrin thrombus. Defects in platelets as well as inherited deficiencies of coagulation factors including fibrinogen...

glanzmann's thrombasthenia (gt) is a rare, genetically inherited platelet disorder in which the platelet glycoprotein iib/iiia (gp iib/iiia) complex is either deficient or, dysfunctional. the incidence is about 1 in 1,000,000. this case report deals with a 4 year-old girl diagnosed with gt presenting with dental caries and periapical lesions in the primary mandibular first molars. to provide th...