in this study, different derivative spectrophotometric methods are proposed for the simultaneous determination of chlorpheniramine maleate (cp), phenylephrine hcl (pe) and phenylpropanolamine hcl (pp) in their ternary mixtures and in pharmaceutical dosage forms. spectra of single component and ternary mixtures of various concentrations and combinations from zero- to fourth-derivation were obtai...

In this paper‎, ‎a modern method is presented to solve a class of fractional optimal control problems (FOCPs) indirectly‎. ‎First‎, ‎the necessary optimality conditions for the FOCP are obtained in the form of two fractional differential equations (FDEs)‎. ‎Then‎, ‎the unknown functions are approximated by the hybrid functions‎, ‎including Bernoulli polynomials and Block-pulse functions based o...

there are several varieties of edge detection method. edge detection and edge enhancement techniques play an essential role in interpreting potential field data. some of common methods are: tilt angle filter (ta), total horizontal derivative of tilt angle filter (thdt), theta filter, tdx filter, hyperbolic tilt angle (hta). these filters maximum values are when facing with the edge of an anomal...

In this study, novel near-infrared and attenuated total reflectance mid-infrared spectroscopic methods coupled with multivariate data analysis were established enabling the determination of thymol, rosmarinic acid, and the antioxidant capacity of Thymi herba. A new high-performance liquid chromatography method and UV-Vis spectroscopy were applied as reference methods. Partial least squares regr...

Two simple, accurate, sensitive and reproducible methods have been developed and subsequent validated for the determination of Sildenafil citrate (SC) in presence of its impurities “1-methyl-4-nitro-3-n-propyl-5pyrozole Carboxamide (MNC), 4-amino-1-methyl-3-n-propyl-5-pyrazole Carboxamide (AMP), 4-(2-ethoxy benzoyl amino)-1-methyl-3-n-propyl-5-pyrazole Carboxamide (EMC) and 5-(2-ethoxyphenyl)-1...

a green and efficient one-pot, four-component synthesis of 6-amino-4-aryl-3-methyl-2,4-dihydropyrano[2,3- c ]pyrazo-carbonitrile derivatives catalyzed by borax in water is described. this method provides several advantages such as environmental friendliness, shorter reaction time, excellent yields, and simple workup procedure. the in vitro cytotoxic activity of the synthesized test compounds wa...