Objective(s) Sickle cell disease is a genetic disorder characterized by chronic haemolytic anaemia. Haemoglobin S containing red blood cells may be susceptible to oxidative stress due to imbalance between production of reactive oxygen species and the countering effect of the various antioxidants present in the body. Materials and Methods We evaluated some antioxidant enzymes which include gl...

OBJECTIVE: Low-grade systemic inflammation is associated with an increased risk of type 2 diabetes. C-Reactive Protein (CRP), an acute phase protein produced by hepatocytes, may be associated with diabetes. This study aimed to compare serum levels of CRP in women with gestational diabetes mellitus (GDM), impaired glucose tolerance test and control subjects. MATERIALS AND METHODS: In this ca...

in  this  study  we  determined  the  frequency,  sensitivity  and  specificity  of  anti  cyclic citrullinated peptides (anti-ccp) igg antibody, total rheumatoid factor (rf-t), and rf isotypes in iranian patients with rheumatoid arthritis (ra) and their association with age, clinical and serological parameters. anti-ccp and rf-t and rf isotypes level were measured in 418 patients and 399 healt...

abstract       background and objectives: diabetes induced oxidative stress plays an important role in pathological damage to the heart and liver by increased production of extracellular matrix. it is thought that the use of medicinal plants, particularly portulaca oleracea. l and regular exercise are effective. the aim of this study was to evaluate the effects of portulaca oleracea. l consumpt...

background and objectives: coronary artery disease (cad) is regarded as the leading cause of morbidity and mortality around the world. diabetes mellitus (dm) is associated with the development of cad and increased risk of morbidity and mortality. the goal of this study was to assess the association of tumor necrosis factorα (tnf-α) and high sensitivity c-reactive protein (hscrp) with cad severi...

background: in most of the studies, the association of vascular events is limited to migraine with aura or it is stronger in this group, whereas the link between migraine without aura (mo) and vascular events remained uncertain. therefore, we decided to evaluate endothelial function by chemical and functional markers of endothelium in mo and compare with normal population. methods: in this stud...