Abstract Mycobacterium tuberculosis contains diverse immunologically active components. This study investigated the biological function of a newly identified component, Rv1654, with potential to induce apoptosis in macrophages. Recombinant Rv1654 induced macrophage caspase‐9/3‐dependent manner through production reactive oxygen species (ROS) and interaction Toll‐like receptor 4. In addition, tu...

Background and Objectives: Strenuous exercises have been shown to induce inflammation. However, consumption of products rich in antioxidants such as vitamin C may enhance this effect. The purpose of this study was to assess effects of vitamin C supplementation on C-reactive protein, lactate and blood pressure following resistance exercise in overweight men. Materials and Methods: In a randomiz...

C-reactive protein (CRP) response was studied in 44 patients with acute angina pectoris admitted to the coronary care unit. 71 % of patients with acute myocardial infarction (MI)had positive CRP test while 73% of patients presumed to have unstable angina pectoris had negative CRP test. This test can be helpful in differentiating between acute MI and unstable angina pectoris.

discoidin domain receptor (ddr) is a new member of the receptor tyrosine kinase family. there are two isoforms of discoidin domain receptor (ddr), ddr1 and ddr2. these receptors play a major role in the adhesion, motility and cell proliferation. due to the important role of ddr2 in the development of tumor extension, this receptor is pivotal in the field of carcinogenesis. the aim of this study...

objective: low-grade systemic inflammation is associated with an increased risk of type 2 diabetes. c-reactive protein (crp), an acute phase protein produced by hepatocytes, may be associated with diabetes. this study aimed to compare serum levels of crp in women with gestational diabetes mellitus (gdm), impaired glucose tolerance test and control subjects. materials and methods: in this case c...

background: stroke is one of the leading causes of mortality and long-term morbidity. the aim of the present study was to determine the ability of baseline serum c-reactive protein (crp) and white blood cell count (wbc) values in predicting the outcome of acute ischemic stroke (ais). methods: this study consisted of patients with first ais referred to poursina hospital, rasht, iran. severity of...

introduction: sudden sensorineural hearing-loss (ssnhl) patients constitute approximately 2–3% of referrals to ear, nose and throat (ent) clinics. several predisposing factors have been proposed for this condition; one of which is vascular disorders and perfusion compromise. in this research the atherosclerotic changes and their known risk factors are studied in ssnhl patients.   materials and ...

background: pregnancy is associated with unfavorable metabolic profile, which might in turn result in adverse pregnancy outcomes. the current study was designed to evaluate the effects of calcium plus vitamin d administration on metabolic status and pregnancy outcomes in healthy pregnant women. methods: this randomized double‑blind placebo‑controlled clinical trial was performed among 42 pregna...

background: considering the existence of controversies about the predictive value of inflammatory markers for cardiovascular disease (cvd), we aimed to compare the level of high?sensitivity c?reactive protein (hs?crp) and interlukin?6 (il?6) level in chronic hemodialysis (hd) patients with and without cvd. materials and methods: in this historical cohort study, hd patients with and without cvd ...