background:  intravenous  recombinant  tissue plasminogen  activator  (rt-pa) is an approved  treatment for acute ischemic stroke within 4.5 h of symptoms onset. decompressive craniectomy (dc) has been  shown  as an effective  therapeutic  modality in malignant  middle cerebral  artery (mca) infarction. as rt-pa could result in hemorrhagic  complication during or after any surgery dc may be ass...

Abbreviations: APTT 5 activated partial thromboplastin time; ASSENT 5 Asessment of the Safety and Efficacy of a New Thrombolytic Agent; CI 5 confidence interval; FTT 5 Fibrinolytic Therapy Trialists’ Collaborative Group; GISSI 5 Gruppo Italiano per lo Studio Streptokinasi nell’Infarto Miocardico; GP 5 glycoprotein; GUSTO 5 Global Utilization of Streptokinase and TPA (alteplase) for Occluded Cor...