OBJECTIVES The purpose of the study was to identify predictive factors of tumor response to preoperative chemoradiotherapy for rectal adenocarcinoma. METHODS Ninety-eight patients with nonmetastatic rectal adenocarcinoma received preoperative concurrent chemoradiotherapy and underwent mesorectal excision. After treatment, tumor response according to tumor regression grade were evaluated. The ...

BACKGROUND Although mucinous adenocarcinoma has been recognized for a long time, whether it is associated with a poorer prognosis in colorectal cancer patients is still controversial. Many studies put emphasis on mucinous adenocarcinoma containing mucin component ≥50%. Only a few studies have analyzed cases with a mucin component <50%. OBJECTIVES This study aimed to analyze the prognostic val...

PURPOSE Transanal endoscopic microsurgery provides a minimally invasive alternative to radical surgery for excision of benign and malignant rectal tumors. The purpose of this study was to review our experience with transanal endoscopic microsurgery to clarify its role in the treatment of different types of rectal pathology. METHODS A prospective database documented all patients undergoing tra...

UNLABELLED Prostate adenocarcinomas present a high risk of metastasis. We report a case of an atypical prostate cancer metastasis. A male patient presented a prostatic adenocarcinoma treated by surgery. A biological recurrence was discovered during the follow-up by an increased rate of Prostate Specific Antigen (PSA) and was treated by hormonotherapy. Several months later, there was a re-increa...

L.B. is a 68-year-old Hispanic man who presented with hematochezia, narrowed stools, and unintentional weight loss over 4 months. A colonoscopy in May 2019 revealed 6-cm, nonobstructing, fungating rectal mass 8 cm from the anal verge. Biopsy confirmed moderately differentiated, invasive adenocarcinoma. Cross-sectional computed tomography (CT) abdominal magnetic resonance imaging (MRI) did not s...

A remote vaginal metastasis from a colo-rectal carcinoma is extremely rare. Only few cases have been described in the literature. The radiological appearances of a vaginal metastasis from colon-rectal cancer have not been extensively investigated. We report the MRI findings with clinical and pathological correlations of a remote and isolated vaginal metastasis revealing a mid-sigmoid adenocarci...

This report is of a 44-year-old woman with an α -foetoprotein–producing rectal adenocarcinoma. At presentation, her serum α-foetoprotein was 158,334 μg/L, and investigation excluded other causes, such as gynaecological malignancy, hepatocellular carcinoma, germ cell tumour, or hepatoid adenocarcinoma. The patient developed early distant metastasis despite treatment with 5-fluorouracil-based che...

Cutaneous metastases of rectal adenocarcinoma is a rare phenomenon. We present a 65 year-old man with a painless nodule on the scrotal skin. Excisional biopsy of the nodules revealed a metastasis from rectum adenocarcinoma. Afterwards, the left scrotum was treated with a radiation therapy and the patient also received a salvage chemotherapy. The patient is still alive without any distant metast...

There has been a high local recurrence rate in rectal cancer. Besides improvements in surgical techniques, both neoadjuvant short-course radiotherapy and long-course chemoradiation improve oncological results. Approximately 40-60% of rectal cancer patients treated with neoadjuvant chemoradiation achieve some degree of pathologic response. However, there is no effective method of predicting whic...

A 41-year-old woman, complaining of minimal vaginal oozing, was diagnosed as rectal cancer with direct infiltration into the vagina in a previous hospital. She was referred to our hospital for further diagnostic workup. Colonoscopy (Fig. 1; note that a color version of this figure is available as supplementary data at http://www.jjco. oxfordjournals.org) showed well-differentiated adenocarcinom...