This document contains the definitions of infertility and recurrent pregnancy loss as defined by the Practice Committee of the American Society for Reproductive Medicine. It replaces the document titled, "Definitions of Infertility and Recurrent Pregnancy Loss," last published in 2008, Fertil Steril 2008;90(Suppl 3):S60.

OBJECTIVE To measure serum leptin and insulin levels in women with recurrent pregnancy loss using modified methods of High Performance Liquid Chromatography (HPLC), and to examine their influence on recurrent loss at different pregnancy trimesters. METHODS A case control study was conducted from, 1 September 2008 to 30 December 2009 in the Obstetric and Gynecological Department-Al-Khadimiya T...

background: immunological factors are important in pregnancy loss because of the interaction between mother and fetus. t-regulatory cells as the component of humeral immune response play important role in the fetu-maternal interface. one of the regulatory mechanisms for these cells is mediated by antigen independent co-stimulatory signals and interaction of cytotoxic t-lymphocyte antigen 4 (b7/...

OBJECTIVE To study the relationship between semen quality and pregnancy loss in a cohort of couples attempting to conceive. DESIGN Observational prospective cohort. SETTING Not applicable. PATIENT(S) Three hundred and forty-four couples with a singleton pregnancy observed daily through 7 postconception weeks of gestation. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Association betwe...

BACKGROUND Circulating microparticles are markers of cell activation associated with various prothrombotic states. As hypoxia due to uteroplacental thrombosis is considered to be one of the causes of pregnancy loss, microparticles may be associated with pregnancy loss, in addition to, or as part of, other procoagulant states such as antiphospholipid syndrome or hereditary thrombophilias. The ob...

background: normal pregnancy is thought to be dependent on th2 deviation, while recurrent pregnancy loss (rpl) and pre-eclampsia (pe) appear to be biased toward the th1 immune response. it is believed that the soluble form of cd30 (scd30) is an index of th2 immune response or modulator of th1/th2 responses. objective: the aim of this study was determination of the scd30 level in rpl and pe pati...