This study assesses the relation between age related macular degeneration (ARMD) and age, sex and occupation. It is designed as a retrospective study conducted on patients presenting to the Eye Polyclinic "Dr. L. Pavicević", Rijeka, Croatia, during the years 1995, 2000 and 2005, and included total of 6617 patients. The number of patients diagnosed with ARMD, their age and sex distribution, as w...

Thus, we are again left with a chicken-and egg situation: Is disrupted Ca2+ signalling, reduced mTOR activity and increased autophagy found in SOD2-/- cells because there are more senescent cells in the examined population? Or is any of these factors the culprit that triggers senescence in the first place? While the answer to these questions still eludes us, the study from Campisi and colleague...

BACKGROUND Cultural interventions to decrease substance abuse must be introduced and evaluated. METHODS Change in risk and protective factor ratings from a brief cultural school-based program were measured. RESULTS Students demonstrated significant improvements in school commitment, self esteem, and perceived harm of drugs. These changes correlated with decreased report of drug use. DISCU...

Sports concussion is a major problem that affects thousands of people every year. Concussion-related neurometabolic changes are thought to underlie neurophysiological alterations and post-concussion symptoms, such as headaches sensitivity light noise, disabilities concentration tiredness. The injury triggers complex cascade involving multiple mechanisms. There pharmaceutical treatments target o...