INTRODUCTION Linezolid may cause adverse effects such as thrombocytopenia, which were found to be dependent on receiving linezolid for longer than 2 weeks. There are limited studies concerning the safety and timing of linezolid-related adverse effects in children. Objective of this study was to evaluate the incidence of adverse effects associated with linezolid, with especially focusing on the ...

In a clinically monitored surveillance of adverse drug reactions in a sample of 186 indoor patients in a general hospital over an average hospital stay of about two weeks, the following points were noteworthy. 32.8% of the patients reported side-effects and of these 79.3% were of mild to moderate intensity.Side-effects could be easily managed by specific antidotes and reassurance and permitted ...

The complexity of antiretroviral therapy, coupled with the lifelong duration of treatment, presents the need for extensive management of drug interactions and adverse effects. This article includes an extensive discussion of drug interactions involving antiretroviral agents and other medications (eg, antibiotics, oral contraceptives, H2 antagonists, and lipid-lowering agents) commonly used in i...

background: inherent toxicity of cytotoxic drugs is the basis for their potential adverse risks from occupational exposure to the nursing staff. in iran, chemotherapy regimens are prescribed and administered according to the world updated protocols. but little is done regarding the protective standards in this field. methods: an observational cross-sectional survey was conducted among nurses wh...

Accessible online at: www.karger.com/journals/res Drug-induced side effects are a very common medical problem. Their prevalence has not been systematically assessed, but there are reports of approximately 2% adverse reactions among hospitalized patients [1]. Among all adverse reactions to drugs which lead to only mild symptoms and which are successfully treated by simply withdrawing the drug in...

We define an adverse drug reaction as "an appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product." Such reactions are currently reported by use of WHO's Adverse Reaction Te...

Introduction Although the local adverse effects of ophthalmic drugs, including allergic reactions, are well recognized, less is known about the systemic side- effects of eye drops, especially during pregnancy, breast-feeding and early childhood. Ophthalmologists should also be aware of unusual, in some cases even life-threatening, effects of commonly used eye drops. Conclusion This brief revi...

haemovigilance is a system with standard program to cover the entire transfusion chain, monitor, evaluate and analyse the data to improve patients’ safety. we report the implemented haemovigilance system in hospitals and transfusion reactions (tr) in iran. methods and materials: this was a prospective descriptive study. the national reporting system for transfusion incidents was introduced in j...

The direct oral anticoagulant rivaroxaban is useful in various indications that include venous deep vein thrombosis prophylaxis/treatment after knee/hip replacement surgery and prevention of stroke in patients with non-valvular atrial fibrillation. Its mechanism of action has been mostly associated with hemorrhage-related adverse effects; thus a number of non-hemorrhage-related adverse effects ...

drug induced dystonic reactions are among common presentations of patients in emergency departments, and typically occur with antidopaminergic agents as their extra-pyramidal side effects. dystonic reactions usually occur within the first few hours or days after commencing a drug or dose increase. unlike other extra-pyramidal side effects, a patient may experience acute dystonic reactions (adrs...