نتایج جستجو برای: renoprotective

تعداد نتایج: 1575  

Journal: :Journal of the American Society of Nephrology : JASN 2009
Satish P RamachandraRao Yanqing Zhu Timothy Ravasi Tracy A McGowan Irene Toh Stephen R Dunn Shinichi Okada Michael A Shaw Kumar Sharma

Although several interventions slow the progression of diabetic nephropathy, current therapies do not halt progression completely. Recent preclinical studies suggested that pirfenidone (PFD) prevents fibrosis in various diseases, but the mechanisms underlying its antifibrotic action are incompletely understood. Here, we evaluated the role of PFD in regulation of the extracellular matrix. In mou...

Journal: :Hypertension 2008
Matthew R Weir

If activated vitamin D supplementation is renoprotective, is it because of suppression of the parathyroid hormone (PTH) or selective vitamin D receptor activation? In the present issue of Hypertension, Alborzi et al1 present the results of a well-done prospective clinical trial to evaluate the effects of short-term (1-month) treatment with activated vitamin D (paricalcitol) on blood pressure, b...

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