The aim of the present study was to prepare an oral tablet from liquid yogurt by reforming the physical properties for easy transportation, long-term storage and also as a complementary dairy product in case of nutrient deficiency. The liquid fresh yogurt was lyophilized at -40°C and 0.03 mTor pressure. The dry powder was homogenized by a 12 mesh size sieve. Some tests such as Carr's compressib...

In the present study, novel co-processed superdisintegrants were developed by solvent evaporation method using crospovidone and croscarmellose sodium in the different ratios (1:1, 1:2 & 1:3) for use in the fast dissolving tablet formulations. The developed excipients were evaluated for angle of repose, Carr’s index and Hausner’s ratio in comparison with physical mixture of superdisintegrants. T...

In this study the physical and thermal properties of baobab (Adansonia digitata) fruit pulp powder which are essential for designing engineering processes, material handling, storage, equipment design and fabrication were determined. The physical properties, namely, mean particle size, bulk density, true density and porosity were determined. Also, angle of repose and coefficient of friction wer...

[1] Mechanistic models for sediment transport on hillslopes are needed for applications ranging from landscape evolution to debris-flow hazards. Progress has been made for soil-mantled landscapes; however, little is known about sediment production and transport in bedrock landscapes that often maintain a patchy soil mantle, even though slopes exceed the angle of repose. Herein we investigate th...

Purpose: To prepare and evaluate colon specific drug delivery system of diclofenac sodium for highly localized delivery to the colon. Methods: The colon specific drug delivery system was prepared as matrix-type microspheres using Ethyl Cellulose (EC), Cellulose Acetate Phthalate (CAP), and Eudragit L 100-55 by the Solvent Evaporation Method. Microspheres were evaluated for physical properties l...

Flowability - as measured by hopper discharge rate, angle of repose and Carr's index (CI) - of surface modified microcrystalline cellulose granules was investigated experimentally. Three-dimensional simulations of the granule flow were performed, using the discrete element method (DEM), including either sliding and rolling friction or sliding friction and cohesion in the model. Granule surface ...

We calculated topographic gradients over the surface of the Moon at a 25 m baseline using data obtained by the Lunar Orbiter Laser Altimeter (LOLA) instrument onboard the Lunar Reconnaissance Orbiter (LRO) spacecraft. The relative spatial distribution of steep slopes can be reliably obtained, although some technical characteristics of the LOLA dataset preclude statistical studies of slope orien...

Objective: The aim of this study was to develop a tablet formulation of Wat Pho hypnotic formula, a classical Thai traditional hypnotic drug. In addition, a preformulation study and physical properties of the finished products were investigated to select the best formulation for further study. Methods: Tablets of the six formulations (D1-D6) were prepared by the direct compression method. The p...

Article history: Received on: 09/07/2013 Revised on: 16/09/2013 Accepted on: 03/10/2013 Available online: 31/10/2013 The aim of the study was to develop a formulation of Ticagrelor 90 mg tablets that is equivalent to the reference product using similar excipients to match the in-vitro dissolution profile. A compressed coated tablet was formulated consisting of Ticagrelor and excipients conformi...