Tertiary treatment of wastewater with ozone is a promising technique for removing residual micropollutants that remain after secondary biological treatment. We monitored the performance of a full-scale ozonation reactor on a sewage treatment plant in Switzerland with a screening battery of bioassays. Six toxicity endpoints were selected that covered non-specific toxicity, as well as selected re...

Determination of drug residues in food is of great importance due to their toxicity. Long-term exposure with low level of drug residues could be important, especially in children. Based on document study, oxytetracycline (OTC) is a prophylaxis and treatment agent for great number of diseases and possesses a broad spectrum activity against many pathogenic organisms and can be toxic or cause alle...

Pest management is being confronted with immense economic and environmental issues worldwide because of massive utilization over-reliance on pesticides. The non-target toxicity, residual consequence, challenging biodegradability these synthetic pesticides have become a serious concern, which urgently requires the alternative prompt adoption sustainable cost-effective pest control measures. Incr...

Hump-nosed viper (HNV) which compromises ‘Hypnale hypnale’, ‘H. zara’ and nepa’ is recognized as a highly venomous snake are the commonest cause of snakebite envenoming in Sri Lanka. It has been earlier identified resulting only minor or local whereas, now known to serious systemic toxicity fatalities. Here we report case 62 year old female presented with bite who developed Microangiopathic Hae...

A series of bioassays were conducted to determine the relative toxicities and residual activities of insecticides labeled for use in blueberry (Vaccinium corymbosum L.) on natural enemies, to identify products with low toxicity or short duration effects on biological control agents. In total, 14 insecticides were evaluated using treated petri dishes and four commercially available natural enemi...

The aim of this study was to test the effect of Streptomyces scabies on the degradation of Gramonol herbicide in order to reduce its residual toxicity. Four isolates of S. scabies (St1, St2, St3, and St4) showed different ability to degrade the gramonol in vitro and in soil. They varied in their potential ability to degrade Gramonol in vitro after 5 days incubation, and after 35 days post herbi...

The persistence of polychlorinated biphenyl (PCB) Aroclor 1248 in soils and sediments is a major concern because of its toxicity and presence at high concentrations. In this study, we developed an integrated remediation system for PCBs using chemical catalysis and biodegradation. The dechlorination of Aroclor 1248 was achieved by treatment with bimetallic nanoparticles Pd/nFe under anoxic condi...

A series of bioassays were conducted to determine the relative toxicities and residual activities of insecticides labeled for use in blueberry (Vaccinium corymbosum L.) on natural enemies, to identify products with low toxicity or short duration effects on biological control agents. In total, 14 insecticides were evaluated using treated petri dishes and four commercially available natural enemi...

The purpose of this study was to investigate the efficacy and safety of the monoclonal antibody, rituximab, in relapsed or refractory hairy cell leukemia (HCL). Fifteen patients with relapsed or primary refractory HCL after nucleoside analogs received rituximab 375 mg/m2 weekly for a total of 8 planned doses. An additional 4 doses could be administered to responders who had not achieved complet...

Fludarabine was used to treat 68 patients with previously treated chronic lymphocytic leukemia (CLL). Nine (13%) patients achieved a complete remission and 30 (44%) a partial remission. The response rates for Rai stages 0 to 2, 3, and 4 were 64%, 58%, and 50% respectively. Seventeen (43%) of the 40 Rai stage 1 to 3 patients and four (19%) of the Rai stage 4 patients returned to Rai stage 0. Sur...