Results Between 2009 and 2010, Multiplex PCR / RT-PCR detected respiratory viruses in 111 (54.7%) of 203 samples. Single virus was detected in 44.8% (91/203) and virus co-infections were observed in 9.9% (20/203). Rhinovirus (40.5%), human Respiratory Syncytial virus (hRSV; 27.9%), and Influenza A virus (9.0%) were the most frequently detected viruses. Adenovirus and human Metapneumovirus were ...

Molecular diagnostic tests have greatly increased our understanding of the role of viruses in pneumonia, and findings indicate that the incidence of viral pneumonia has been underestimated. The most commonly identified viruses in community-acquired pneumonia (CAP) are influenza, rhinovirus, respiratory syncytial virus (RSV), and human metapneumovirus (hMPV). Viral infections are common in adult...

BACKGROUND Various viruses are known to be associated with pneumonia. However, the impact of viral infections on adult pneumonia mortality remains unclear. This study aimed to clarify the effect of virus infection on pneumonia mortality among adults stratified by virus type and patient comorbidities. METHODS This multicentre prospective study enrolled pneumonia patients aged ≥15 years from Se...

Specific antibodies against infections most relevant to patients with primary immunodeficiency diseases are not routinely evaluated in commercial polyclonal immunoglobulin preparations. A polyclonal immunoglobulin prepared from plasma of donors having high neutralizing antibody titers to respiratory syncytial virus (RSV) was studied for the presence of antibody titers against seven additional r...

Acute respiratory viral infections are the most common human diseases. Symptoms of infection vary from a slight cold to critical condition requiring artificial lung ventilation and support cardiovascular system. Main risk factors severe disease include high load, co-infection with other pathogens, age 0 2 years older than 65 years, immunodeficiency. Cardiac manifestations usually caused by indi...

BACKGROUND Surveillance of influenza-like illness (ILI) in Central Africa began only recently, and few data are therefore available on the circulation of influenza virus and other respiratory viruses. In Gabon, a Central African country, we established a surveillance network in four major towns in order to analyze cases of ILI among patients who visited health centers between March 2010 and Jun...

BACKGROUND Viral interaction in which outbreaks of influenza and other common respiratory viruses might affect each other has been postulated by several short studies. Regarding longer time periods, influenza epidemics occasionally occur very early in the season, as during the 2009 pandemic. Whether early occurrence of influenza epidemics impacts outbreaks of other common seasonal viruses is no...

Background: Both influenza A virus (IAV) and respiratory syncytial virus (RSV) cause acute respiratory infection (ARI) in infants and young children. This study was conducted to determine Influenza A virus and its co infection with RSV among the hospitalized children with ARI. Methods: A total of 153 throat samples of the hospitalized young children aged between below one year and 5 years with...

The Bartels respiratory virus panel detection kit is an indirect fluorescent-antibody (IFA) method that uses pooled and individual antisera for tissue culture confirmation of seven respiratory viruses. We evaluated these reagents for detecting viral antigen in shell vial cultures and by direct staining of cells from respiratory specimens. The isolation from 254 specimens of respiratory viruses ...