pH-responsive perylene-ended amphiphilic homopolymers can self-assemble into flower-like structures by pH-adjustment. Both the π-π stacking of perylene end groups and the electrostatic repulsion effect of the polymer chains contribute to the pH-responsive self-assembly in aqueous solution.

A novel tellurium-containing polymer micelle system is reported to be responsive to 100 μM H2O2 and can undergo a series of morphological changes. The polymer micelles also respond to 2 Gy gamma radiation, which is the exact dosage a patient receives per day for clinical radiation therapy.

Understanding the complex behavior and dynamics of cellular membranes is integral to gain insight into division fusion processes. Bottom-up synthetic cells are as a platform for replicating probing behavior. Giant polymer vesicles more robust than liposomal counterparts, well having broad range chemical functionalities. However, stability membrane can prohibit dynamic processes such phase separ...

A reversible electrochemical switching has been displayed at smart polymer brush interfaces, which was responsive to temperature, ionic strength and pH stimuli, independently or simultaneously.

A simple biomimetic ionic gate has been developed by modifying lead(II) ion responsive DNAzymes onto the inner surface of ion-etched polymer nanochannels.

Environmentally responsive poly(N-isopropylacrylamide) brushes were grafted from the surface of polymer particles or flat surfaces in order to generate reversible hydrophilic and hydrophobic surfaces. The use of atom transfer radical polymerization was demonstrated for the grafting of polymer brushes as it allows efficient control on the amount of grafted polymer. The polymer particles were gen...

Responsive polymer-based materials are capable of altering their chemical and/or physical properties upon exposure to external stimuli. These materials have been intensively studied over the years for a diverse range of applications, e.g., for on-demand drug delivery, tissue generation/repair, biosensing, smart coatings, and artificial muscles. Here, we review recent advances in the areas of se...

Surfaces with end-grafted, nanopatterned polymer brushes that exhibit well-defined feature dimensions and controlled chemical and physical properties provide versatile platforms not only for investigation of nanoscale phenomena at biointerfaces, but also for the development of advanced devices relevant to biotechnology and electronics applications. In this review, we first give a brief introduc...

We report a new thermal targeting method in which a thermally responsive drug carrier selectively accumulates in a solid tumor that is maintained above physiological temperature by externally applied, focused hyperthermia. We synthesized two thermally responsive polymers that were designed to exhibit a lower critical solution temperature (LCST) transition slightly above physiological temperatur...

A UV-responsive polymer was prepared via condensation polymerization of 2-nitrobenzyl(4-(1,2-dihydroxyethyl)phenyl)carbamate and azalaic acid dichloride. When the polymer was irradiated with UV light, the nitrobenzyl urethane protecting group was removed and the deprotected aniline underwent spontaneous 1,6-elimination reactions, resulting in degradation of the polymer. Nanoparticles with encap...