نتایج جستجو برای: retroviral vector
تعداد نتایج: 205424 فیلتر نتایج به سال:
RNA interference (RNAi) is a widely used molecular biology technique to investigate the importance of specific genes in molecular pathways. Since mammalian cells are equipped with endogenous RNAi processing machinery, it has become common practice to transfect constructs that encode for short hairpin RNAs that are then cleaved to form the active RNAi sequences that bind to target mRNAs. Given t...
Background : Highly active anti-retroviral therapy (HAART) includes the use of three or more anti-retroviral drugs with proven in controlling AIDS. The aim of this study was to investigate adherence and process of anti-retroviral therapy in patients refereed to Isfahan Behavioral Consultation Center from 1999 to 2009. Methods : This study was a cross-sectional study and therapeutic process ...
Currently cancer gene therapy using recombinant DNA technology provides a new and promising treatment models aim to destruction the malignant growth (Qian et al., 2004; Xing et al., 2011). A variety of gene therapy-based anticancer strategies have been tested in animal tumor models, including selective activation of prodrugs, genetic immunotherapy, antiangiogenic actions and replacement of tumo...
A high titer retroviral vector was used to transfer a human adenosine deaminase (h-ADA) cDNA into murine bone marrow cells in vitro. The h-ADA cDNA was linked to the retroviral promoter, and the vector also contained a neomycin phosphotransferase gene as a selectable marker. Infected marrow was transplanted into syngeneic W/W’ recipients, and h-ADA expression was monitored for 5.5 months. Sever...
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