Cytoplasmic rRNA from the yeast mutant, mod5-1 is deficient in the modified base isopentenyladenosine and consequently migrates differently from isopentenylated wild type tRNAs on certain chromatographic systems. To determine if the mod5-1 mutation affects mitochondrial tRNA structure, the migration of mitochondrial tRNA from mod5-1 and wild type cells has been compared by reverse-phase chromat...

Synthetic and analytical approaches were used to characterize the tumor-localizing components of the porphyrin preparation, hematoporphyrin derivative. From studies involving aqueous and nonaqueous gel exclusion and reverse-phase chromatography, we conclude that localization is mediated by hematoporphyrin derivative components which are among the most hydrophobic in the preparation. This appare...

Synthetic and analytical approaches were used to characterize the tumor-localizing components of the porphyrin preparation, hematoporphyrin derivative. From studies involving aqueous and nonaqueous gel exclusion and reverse-phase chromatography, we conclude that localization is mediated by hematoporphyrin derivative components which are among the most hydrophobic in the preparation. This appare...