نتایج جستجو برای: rhabdoid tumor
تعداد نتایج: 428329 فیلتر نتایج به سال:
Brain tumors represent the most common solid neoplasm in children and second most common pediatric malignancy overall, following leukemia. Outside of infancy, the majority of primary childhood brain tumors occur in the infratentorial compartment and include medulloblastoma, juvenile pilocytic astrocytoma (JPA), ependymoma, and brainstem/ pontine glioma; atypical teratoid rhabdoid tumor (ATRT) i...
Purpose: Atypical teratoid/rhabdoid tumors (AT/RT) are highly aggressive pediatric malignancies characterized by biallelic inactivation of the SMARCB1 tumor suppressor gene. We searched for novel genomic aberrations by investigating the copy number and expression alterations of let-7a3/let-7b microRNA (miRNA) and correlated these with expression of high-mobility group AT-hook 2 (HMGA2) oncoprot...
Malignant rhabdoid tumour (MRT) is a well established aggressive malignant neoplasm occurring in kidney particularly in infants and children. When this type of tumor involves any extrarenal site it is termed malignant extrarenal rhabdoid tumor (MERT). Here we report a case of MERT involving the oral cavity. To the best of our knowledge, apart from us only one oral MERT has been documented. Due ...
Sarcomas of the vulva account for only 1-3% of all vulvar malignancies. Most common vulvar sarcomas are leiomyosarcomas, malignant fibrohistiocytomas, and aggressive angiomyxomas. Malignant rhabdoid tumor (MRT) of the kidney is a distinctive clinicopathological entity that is recognized as a highly aggressive renal tumor of childhood. Extrarenal malignant rhabdoid tumors have been proposed to e...
INTRODUCTION Atypical teratoid rhabdoid tumors are highly malignant neoplasms that present in young children and can grow to a large size. Maximal safe surgical resection is a mainstay of treatment. PRESENTATION OF CASES Two cases of children under the age of two with large tumors involving the supratentorial and infratentorial compartments are presented. A two-staged operative approach combi...
Purpose: Atypical teratoid/rhabdoid tumors (AT/RT) are highly aggressive pediatric malignancies characterized by biallelic inactivation of the SMARCB1 tumor suppressor gene. We searched for novel genomic aberrations by investigating the copy number and expression alterations of let-7a3/let-7b microRNA (miRNA) and correlated these with expression of high-mobility group AT-hook 2 (HMGA2) oncoprot...
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