It has long been recognized that in most inflamed arthritic joints the coagulation system is activated, leading to the local generation of fibrin, and it has long been hypothesized that the local fibrin deposition promotes inflammation and tissue destruction. However, only recently has the direct effect of fibrin on the inflammatory process been seriously investigated, and specific roles assign...

BACKGROUND AND PURPOSE The aim of this study is to analyze the histological composition of acute arterial thrombi and their MRI signals. METHODS Two different types of experimental thrombi, erythrocyte- and fibrin-rich thrombus, were created and injected into an experimentally formed stenotic common carotid artery in swine. MRI of the in vivo and in vitro samples was obtained immediately afte...

Autologous platelet concentrates represent promising innovative tools in the field of regenerative medicine and have been extensively used in oral surgery. Unlike platelet rich plasma (PRP) that is a gel or a suspension, Leukocyte-Platelet Rich Fibrin (L-PRF) is a solid 3D fibrin membrane generated chair-side from whole blood containing no anti-coagulant. The membrane has a dense three dimensio...

An immature tooth with pulpal necrosis and periapical pathology imposes a great difficulty to the endodontists. Endodontic treatment options for such teeth consist of conventional apexification procedure with and without apical barriers. Various materials have been tried as apical matrix in the past. This article demonstrates the newer concept of using platelet rich fibrin membrane as an apical...

BACKGROUND Multirooted teeth offer unique and challenging problems due to the furcation area, creates situations in which routine periodontal procedures are somewhat limited and special procedures are generally required. CASE DETAIL The present case was showing the management of grade II furcation defect by platelet rich fibrin (PRF) and β-Tricalcium phosphate with coronally advanced flap. ...

Secondary alveolar bone grafting is a method that enables an excellent oral rehabilitation of the patients having cleft palate. Many types of bone grafts have been used for reconstruction of the cleft, including autogenous bone and bone substitutes. Platelet-rich fibrin (PRF) has been shown to be effective in grafting the defect. The aim of this presentation is to report the closure of an alveo...

The composition of an evolving arterial thrombus may be a determinant of how effectively pharmacologic agents prevent reocclusion after initially successful thrombolysis. In this study, reoccluding platelet- or fibrin-rich thrombi as delineated by scanning electron microscopy were produced selectively in the femoral arteries of dogs with the use of electrically induced vascular injury or implan...