OBJECTIVES To assess left ventricular systolic and diastolic function in adult patients with cystic fibrosis using radionuclide ventriculography. BACKGROUND Although myocardial fibrosis has been described in autopsy specimens of patients with cystic fibrosis, the possibility that myocardial dysfunction may occur during life in adult patients with cystic fibrosis has not been explored. METHO...

INTRODUCTION To investigate haemodynamic and respiratory changes during lung recruitment and decremental positive end-expiratory pressure (PEEP) titration for open lung ventilation in patients with acute respiratory distress syndrome (ARDS) a prospective, clinical trial was performed involving 12 adult patients with ARDS treated in the surgical intensive care unit in a university hospital. ME...

BACKGROUND AND OBJECTIVES Higher left ventricular volume is associated with death in patients with ESRD. This work investigated the effects of frequent hemodialysis on ventricular volumes and left ventricular remodeling. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The Frequent Hemodialysis Network daily trial randomized 245 patients to 12 months of six times per week versus three times per ...

Beta-blockers are used to treat acquired heart failure in adults, though their role in early muscular dystrophy cardiomyopathy is unclear. We treated 2 different dystrophic mouse models which have an associated cardiomyopathy (mdx: model for Duchenne Muscular Dystrophy, and Sgcd-/-: model for limb girdle muscular dystrophy type 2F) and wild type controls (C57 Bl10) with the beta blocker metopro...

Background: Pulmonary artery acceleration time (PAAT) can be used as a parameter in the evaluation of pulmonary hypertension and aids left ventricular diastolic function (LVDF) analyses. Objective: To assess whether there is correlation between PAAT LVDF parameters individuals with preserved systolic by sex, age, cardiovascular risk factors. Method: Observational cross-sectional study. One hund...

background: early diagnosis of left ventricular mass (lvm) inappropriateness and left ventricular hypertrophy   (lvh) can result in preventing diastolic left ventricular dysfunction and its related morbidity and mortality. this study was performed to determine if diastolic dysfunction   is associated with lvh and inappropriate lvm. methods: one hundred   and twenty five uncomplicated hypertensi...

To assess the long-term changes in cardiac function iu N tomatic patients with severe left veatricuiar dysfunction, left ventricular (clneangiography) and right ventricular (radionuelide angiography) function were assesxd at baseline in 49 patients enrolled in the prevention arm of the Studies of Left Ventricular Dysfuoction. After an average follow-up period of 12.4 months, 30 patients (11 ran...

In pulmonary hypertension and other conditions, such as acute respiratory distress syndrome and left heart failure, right ventricular dysfunction is a prognostic determinant. Therefore, functional parameters pertaining to the right heart alone, i.e. independent of its loading conditions, should be used to quantify right ventricular disease progression and the results of treatment. Two methods t...

Objectives—To investigate right ventricular diastolic function in systemic sclerosis (SSc) and its relation to clinical features of the disease. Methods—Seventy seven unselected SSc patients and 33 healthy subjects were submitted to echocardiography and echo Doppler study to assess left and right systolic as well diastolic function and to estimate maximal arterial systolic pulmonary pressure (P...