The tumor necrosis factor receptor 1 (TNFR1) and the Fas receptor recruit complexes formed by the interactions between RIP kinase, TRADD, FADD and RAIDD — adaptor proteins that contain death domains – which in turn recruit other proteins to initiate signaling [1–5]. To identify proteins associated with the TNF signaling pathway, we performed a yeast twohybrid interaction screen using RIP as bai...

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) (Apo2 ligand [Apo2L]) is a member of the TNF superfamily and has been shown to have selective antitumor activity. Although it is known that TRAIL (Apo2L) induces apoptosis and activates NF-kB and Jun N-terminal kinase (JNK) through receptors such as TRAIL-R1 (DR4) and TRAIL-R2 (DR5), the components of its signaling cascade ha...

STAT3 is a ubiquitous transcription factor that is indispensable during early embryogenesis. To study the functions of STAT3 postnatally, we generated conditional STAT3-deficient mice. To that end, STAT3(lox/lox) mice were crossed with mice expressing Cre under the control of rat insulin II gene promoter (RIP-Cre mice). Immunohistochemical and Western blot analyses showed that STAT3 is deleted ...

Relative ingroup prototypicality (RIP) is an important concept in the ingroup projection model of social discrimination and tolerance. This paper reviews measures of RIP currently in use and critically examines how the notion of relative ingroup prototypicality is captured by statistical tests treating RIP as a single variable. It is concluded that composite measures of RIP imply multiple stati...

The pneumotachometer is currently the most accepted device to measure tidal breathing, however, it requires the use of a mouthpiece and thus alteration of spontaneous ventilation is implied. Respiratory inductive plethysmography (RIP), which includes two belts, one thoracic and one abdominal, is able to determine spontaneous tidal breathing without the use of a facemask or mouthpiece, however, ...

This paper examines the effect of current-induced breaking on the modeling of wave breaking dissipation near rip currents. Simulations using a set of existing wave transformation models are compared to existing laboratory measurements made on a bar/channel topography in the presence of both strong and weak rip currents. The model/data comparisons demonstrate that existing models can effectively...

Scientific T To examine the spatial and temporal variability of rip currents using remote video imaging techniques. T To quantify changes in nearshore circulation and topography in response to varying incident wave conditions at different time scales including; P wave groupiness (time scales of 1-10 minutes), P tidal modulation (time scales of 12h and 24 h) and P wave height fluctuations associ...

In this note, we prove that matrices whose entries are all 0 or 1 cannot achieve good performance with respect to the Restricted Isometry Property (RIP). Most currently known deterministic constructions of matrices satisfying the RIP fall into this category, and hence these constructions suffer inherent limitations. In particular, we show that DeVore’s construction of matrices satisfying the RI...

The restricted isometry property (RIP) has become well-known in the compressed sensing community. Recently, a weaken version of RIP was proposed for exact sparse recovery under weak moment assumptions. In this note, we prove that the weaken RIP is also sufficient for stable and robust sparse recovery by linking it with a recently introduced robust width property in compressed sensing. Moreover,...

In an analysis of 22 of the roughly 100 dispersed 5S rRNA genes in Neurospora crassa, a methylated 5S rRNA pseudogene, Psi63, was identified. We characterized the Psi63 region to better understand the control and function of DNA methylation. The 120-bp 5S rRNA-like region of Psi63 is interrupted by a 1.9-kb insertion that has characteristics of sequences that have been modified by repeat-induce...