INTRODUCTION Endotoxins are one of the etiologic agents involved in the pathogenesis of apical periodontitis. The objectives of this clinical study were to investigate the effects of endodontic treatment by using different irrigants on endotoxins in root canals with pulp necrosis and apical periodontitis and to evaluate the cytotoxic effects. METHODS Thirty-six root canals were selected. Samp...

INTRODUCTION This study examined the effect of different root canal irrigant agitation protocols in the penetration of an endodontic irrigant into dentinal tubules. METHODS Fifty-six human single-rooted teeth were shaped with nickel-titanium instruments, and a final rinse of 5% sodium hypochlorite labeled with 0.2% alizarin red was performed. Specimens were assigned to 7 groups (N = 8) and su...

INTRODUCTION The Self-Adjusting File (SAF) system (ReDent-Nova, Ra'anana, Israel) has been recently introduced for the simultaneous instrumentation and irrigation of root canals. The SAF is claimed to adapt itself three dimensionally to the root canal, including its cross-section. It is operated with a continuous flow of sodium hypochlorite that is delivered into the root canal through the holl...

BACKGROUND There are various microorganisms related to intra and extra-radicular infections and many of these are involved in persistent infections. Bacterial elimination from the root canal is achieved by means of the mechanical action of instruments and irrigation as well as the antibacterial effects of the irrigating solutions. Enterococcus faecalis can frequently be isolated from root canal...

statement of problem: bacterial agents are the primary cause of pulpoperiapical diseases. therefore, an irrigating solution with proper antibacterial ability should be used to eliminate the bacterial agents during canal instrumentation. purpose: the aim of present study was to compare the antibacterial effect of 0.2% chlorhexidine to 0.5% sodium hypochlorite as canal irrigating solutions. mater...

OBJECTIVES MicroCT allows the complex canal network of teeth to be mapped but does not readily distinguish between structural tissue (dentine) and the debris generated during cleaning. The aim was to introduce a validated approach for identifying debris following routine instrumentation and disinfection. METHODS The mesial canals of 12 mandibular molars were instrumented, and irrigated with E...

Endodontic emergencies are associated with pain and swelling which requires immediate diagnosis and treatment. The main causative factors for these emergencies are pulp and peri-radicular pathosis, traumatic injuries, procedural complications; were sodium hypochlorite accidents can occur. The impetus behind a successful root canal treatment relies on a thorough debridement of tissue remnants, b...

OBJECTIVE The aim of this study was to assess in vitro the antimicrobial activity of 2% chlorhexidine gel against Enterococcus faecalis , comparing it to other endodontic irrigants (2% chlorhexidine liquid and 5.25% sodium hypochlorite). STUDY DESIGN Eighty roots of human mandibular premolars were prepared by serial instrumentation technique, autoclaved, and contaminated for 7 days with E fae...

AIMS To compare amount of root canal debris and irrigant extruded apically after irrigants agitation using closed and open chambers. METHODS AND MATERIAL Sixty maxillary central incisors were selected, decoronated, and mounted in preweighed glass vials filled with distilled water. Biomechanical preparation was completed using ProTaper rotary files until number F4 and 1 mL of 3% NaOCl solution...