BACKGROUND Rotator cuff failure after surgery may be attributed to inferior tissue healing properties that result from repetitive cyclic loading during early rehabilitation. Enhancing the biological healing process may reduce the incidence of failures after rotator cuff repairs. HYPOTHESIS Augmentation of rotator cuff tissue using swine small intestine submucosa in a sheep model will improve ...

OBJECTIVE To demonstrate and further determine the incidences of repaired supraspinatus tendons on early postoperative magnetic resonance imaging (MRI) findings in clinically improving patients and to evaluate interval changes on follow-up MRIs. MATERIALS AND METHODS Fifty patients, who showed symptomatic and functional improvements after supraspinatus tendon repair surgery and who underwent ...

OBJECTIVES To analyse the collagen composition of normal adult human supraspinatus tendon and to compare with: (1) a flexor tendon (the common biceps tendon) which is rarely involved in any degenerative pathology; (2) degenerate tendons from patients with chronic rotator cuff tendinitis. METHODS Total collagen content, collagen solubility and collagen type were investigated by hydroxyproline ...

BACKGROUND Literature regarding the outcomes of revision rotator cuff repair is limited. The purposes of the present study were to report the tendon repair integrity and clinical outcomes for a cohort of patients following revision arthroscopic rotator cuff repair and to examine factors related to tendon healing and the influence of healing on clinical outcomes. METHODS Twenty-one of twenty-n...

We have undertaken an in vivo assessment of the tissue metabolism and cellular activity in torn tendons of the rotator cuff. Cellular oxygen consumption was measured in 13 patients undergoing mini-open repair of small, medium, large and massive full-thickness tears. Measurements were also taken from three control patients who were undergoing open stabilisation of the shoulder with grossly norma...

Repair of rotator cuff tears in experimental models has been significantly improved by the use of enhanced biologic approaches, including platelet-rich plasma, bone marrow aspirate, growth factor supplements, and cell- and gene-modified cell therapy. Despite added complexity, cell-based therapies form an important part of enhanced repair, and combinations of carrier vehicles, growth factors, an...

Abstract Calcifying tendinitis is a very common pathology in the shoulder region, which may be acute or chronic. The rotator cuff, particularly supraspinatus tendon, most frequently affected. tendons of cuff undergo natural cycle destruction and regeneration. development calcifying caused by defective tendon repair. Typical chronic course with pain exacerbation, leads to medical presentation. T...

abstract  background: rotator cuff tear is one of the most common causes of shoulder  complaints in the elderly. based on the severity and patient's condition, a variety of  methods applies to manage the tear and surgery is an important method, which could  be done by open or arthroscopic technique. the current study aimed to investigate  and report short-term results of arthroscopic repair of ...

We have used Fourier transform infrared spectroscopy (FTIR) to characterise the chemical and structural composition of the tendons of the rotator cuff and to identify structural differences among anatomically distinct tears. Such information may help to identify biomarkers of tears and to provide insight into the rates of healing of different sizes of tear. The infrared spectra of 81 partial, s...

BACKGROUND Platelet-rich plasma (PRP) contains various growth factors and appears to have a potential to promote tendon healing, but evidence is lacking regarding its effect on human tenocytes from rotator cuff tendons with degenerative tears. HYPOTHESIS Platelet-rich plasma stimulates cell proliferation and enhances matrix gene expression and synthesis in tenocytes isolated from human rotato...