BACKGROUND Although the effectiveness of ginger as an antioxidant agent has been exploited, little human research has been conducted on its activity on male reproductive functions. OBJECTIVE This study was designed to investigate the effects of ginger (Zingiber officinale) on sperm DNA fragmentation (SDF) in infertile men. MATERIALS AND METHODS This randomized double-blind, placebo-controll...

Cord blood is a sample of blood taken from a newborn baby's umbilical cord.Cord blood is collected because it is rich in stem cells content, such as hematopoietic cells, which can be used to treat hematopoietic and genetic disorders. Cord Blood Transplantation has been used in the treatment of over 80 diseases, including leukemia, lymphoma and anemia. Advantages of Cord Blood Treatment: • ...

Background: The aims were to determine the diagnostic accuracy of ultrasound sonography in detecting major structural anomalies on all patients who conceived during a year of infertility treatment [assisted reproductive technology (ART) or non-ART treatments] at the Royan Institute, and to study the outcome of cases with nuchal translucency (NT) ≥ 95th centile in the first trimester of pregnanc...

Background: Microdeletions of the long arm of the chromosome Y are the most common molecular genetic cause of severe infertility in men which affect three regions of AZFa, AZFb and AZFc (Azoospermia factor). These regions contain various genes involved in spermatogenesis. The effect of ethnicity on the patterns of Y chromosome microdeletions has not been extensively studied, particulary in Iran...

Background One of the important complications of assisted reproductive technologies is multiple pregnancy, the aim of the present study was to indentify the risk factors of multiple pregnancy independent of number of transfred embryos. MaterialsAndMethods This retrospective study reviewed the medical records of patients underwent intracytoplasmic sperm injection (ICSI) cycle in Royan Institute ...

chromosome-centric human proteome project (c-hpp) is a recent initiative to rationalize and analyze gene-protein and protein-protein interactions in normal and disease conditions. this initiative is aimed to generate the proteomic atlas explaining the molecular architecture of the human body and was initiated in response to the hurdles identified during analyzing the human genome project (hgp)....

background: to compare a flexible, multi-dose gnrh antagonist protocol with a long gnrh .agonist protocol in poor respo materials and methods: a randomized clinical trial of 70 poor responder patients (35 patients in gnrh antagonist protocol and 35 patients in long gnrh agonist protocol) was performed at royan institute, tehran, iran. both groups were given a fixed dose of human menopausal gona...

stem cells are naïve or master cells. this means they can transform into special 200 cell types as needed by body, and each of these cells has just one function. stem cells are found in many parts of the human body, although some sources have richer concentrations than others. some excellent sources of stem cells, such as bone marrow, peripheral blood, cord blood, other tissue stem cells and hu...

Background The effect of hysteroscopic polpectomy for endometrial polyps during treatment cycles is still debated and further studies are necessary to evaluate beneficial effect of this procedure. MaterialsAndMethods This matched case-control study compared retrospectively 86 women with and without hysteroscopic polypectomy who underwent in vitro fertilization and / or Intracytoplasmic sperm in...