Human RPA (replication protein A), a single-stranded DNA-binding protein, is required for many cellular pathways including DNA repair, recombination and replication. However, the role of RPA in nucleotide excision repair remains elusive. In the present study, we have systematically examined the binding of RPA to a battery of well-defined ssDNA (single-stranded DNA) substrates using fluorescence...

The isoscalar giant dipole resonance structure in Pb is calculated in the framework of a fully consistent relativistic random phase approximation, based on effective mean-field Lagrangians with nonlinear meson self-interaction terms. The results are compared with recent experimental data and with calculations performed in the HartreeFock plus RPA framework. Two basic isoscalar dipole modes are ...

We investigate the effect of many-body electronic correlations on spin Coulomb drag (SCD) beyond the random phase approximation (RPA). We make use of the fully spin-resolved static and dynamical many-body local field factors of the two-dimensional electron gas (2DEG) to improve the calculations of the particle-hole and plasmon-mediated contributions to the SCD. Also, we incorporate in our calcu...

We review self-consistent spectral methods for nuclear matter calculations. The in-medium T −matrix approach is conserving and thermodynamically consistent. It gives both the global and the single-particle properties the system. The T −matrix approximation allows to address the pairing phenomenon in cold nuclear matter. A generalization of nuclear matter calculations to the superfluid phase is ...

Absorbing boundary conditions are often employed in time-dependent mean-field calculations to cope with the problem of emitted particles which would otherwise return back onto the system and falsify the dynamical evolution. We scrutinize two widely used methods, imaginary potentials and gradual attenuation by a mask function. To that end, we consider breathing oscillations of a nucleus computed...

A generalized RPA formalism is presented which treats pp and ph correlations on an equal footing. The effect of these correlations on the single-particle Green function is discussed and it is demonstrated that a self-consistent treatment of the single-particle Green function is required to obtain stable solutions. A simple approximation scheme is presented which incorporates for this self-consi...

The structure of nuclei far off β-stability is investigated by nuclear many-body theory. In-medium interactions for asymmetric nuclear matter are obtained by (Dirac-) Brueckner theory thus establishing the link of nuclear forces to free space interactions. HFB and RPA theory is used to describe ground and excited states of nuclei from light to heavy masses. In extreme dripline systems pairing a...

We derive analytical expressions for the excitation energy of the isoscalar giant monopole and quadrupole resonances in finite nuclei, by using the scaling method and the extended Thomas–Fermi approach to relativistic mean field theory. We study the ability of several non-linear σ − ω parameter sets of common use in reproducing the experimental data. For monopole oscillations the calculations a...

We propose a method for microscopic calculations of nuclear groundstate properties in the framework of density functional theory (DFT). We discuss how the density functional is equivalent to the effective action for the density, thereby establishing a constructive framework for DFT calculations from nuclear forces. The presented approach starts from non-interacting nucleons in a background pote...