objective(s):degradation of sphingosine 1-phosphate (s1p), as a bioactive lipid, or deregulation of its production involves in tumor progression, metastasis and chemoresistance. since the tumor progression effects of s1p and its mechanism in chronic lymphoblastic leukemia and non-small cell lung cancer is not fully understood, we investigated the role and one of the mechanisms of s1p in tumor p...

background: rahbdoid tumor of kidney (rtk) is a childhood rare neoplasm, previously thought as a sarcoma variant of wilms’ tumor, but now is recognized as a distinct pathologic entity. method : we report a pathologically proved case of rtk, associated with brain mass in a 4.5-month-old girl that has referred for gross hematuria. shortly after initiating chemotherapy, because of retractile vomit...