The present experiment was aimed at assessing the application of neostigmine, an acetylcholinesterase (AChE) pseudo-irreversible inhibitor with poor penetration through the hematoencephalitic barrier, and the neurotransmitter acetylcholine (ACh). The experiment was done to evaluate their ability to modulate an infectious disease: tularemia. Mice infected with Franciselle tularensis and exposed ...

a week. The author recommends a dose of up to 4 grains intravenously, and also mentions a few cases of influenzal broncho-pneumonia treated with iodine given intravenously in saline solution. Normal saline is undoubtedly a better diluent than simple water inasmuch as it counteracts the irritation caused by nascent iodine. With this diluent I gave several injections into my left dorsal radial ve...

Methods: Eighty bovine pulp fragments were prepared, and their weight was determined using a precision balance. Each pulp fragment was immersed for 2 hours in a solution/mixture that was based on the following groups: G1 – saline solution; G2 – 0.5% NaOCl; G3 – 1.0% NaOCl; G4 – 2.5% NaOCl; G5 – 17% EDTA; G6 – 0.5% NaOCl+17% EDTA; G7 – 1.0% NaOCl+ 17% EDTA; and G8 – 2.5% NaOCl+17% EDTA. The fina...

Memory of a novel object was examined in saline (Sal) and scopolamine (Scopo) treated rats (1.0 mg/kg). Scopo rats showed lower overall exploration time than Sal rats, resulting mainly from shorter durations per contact. In a second exposure to the same object, after 1 min or 20 min interval, both groups displayed marked decrease of exploration indicating between-session habituation. The shorte...

Amplicon sequencing has been the method of choice in many high-throughput DNA sequencing (HTS) applications. To date there has been a heavy focus on the means by which to analyse the burgeoning amount of data afforded by HTS. In contrast, there has been a distinct lack of attention paid to considerations surrounding the importance of sample preparation and the fidelity of library generation. No...

Metallic surfaces and particles can have dramatic effects on fluorescence, including localized excitation, increased quantum yields, increased photostability and increased distances for resonance energy transfer (RET), and directional emission. While all these effects have not yet been realized in a single system, metal-enhanced fluorescence promises to provide the next generation of high sensi...

OBJECTIVE To investigate if the addition of dexmedetomidine to meperidine in a patient-controlled analgesia (PCA) device would reduce postoperative meperidine consumption when compared with meperidine alone. METHODS Forty patients scheduled for elective abdominal surgery under general anesthesia in Suleyman Demirel University Medical School, Isparta, Turkey between February and September 2006...