Oncocytomas of salivary gland are benign tumors composed exclusively of oncocytic cells. Majority of them occur in parotid gland and have excellent prognosis following complete excision. They should be differentiated from other salivary gland tumors with more prominent oncocytic component and nodular oncocytic hyperplasia. Herein we present a case of oncocytoma of parotid gland in a 48 year old...

This study was carried out to study the histopathological spectrum of salivary gland tumors and to know their pattern of distribution. A combination study was done with retrospective data of eight years from june 2001 to may 2009 and prospective data of two years from June 2009 to June 2011 in the department of pathology of our hospital. The study was duly approved by Hospital Ethical Committee...

Estrogen receptors (ERs) expression has been studied in salivary gland tumors, however, there are conflicting results regarding its expression in the literatures. The aim of this study was to investigate the expression of estrogen receptors protein (ERs) in pleomorphic adenoma (PA) and mucoepidermoid carcinoma (MEC) of salivary glands using immunohistochemistry. 35 cases of intraoral minor sali...

Myoepithelial cells are smooth muscle like cells having epithelial origin. They are present in salivary glands, mammary gland, sweat gland and lacrimal gland. Myoepithelial cells are stellate or spindle shaped with 4 to 8 cytoplasmic processes. They play vital role during expulsion of saliva and regulates the electrolytic exchange. They also act as tumor suppressor and are considered very impor...

Parapharyngeal space (PPS) is one of potential space of head and neck region and due to its hidden anatomical location, pathologies arising in this space are late to diagnose. This inverted pyramidal space was termed previously as pterygomaxillary space, lateral pharyngeal space and pharyngio-maxillary space. Parapharyngeal space is the current term that has come to stay because of indistinct i...

UNLABELLED Salivary gland tumors constitute a highly heterogeneous histopathologic group. There are few epidemiological studies of large series of benign and malignant salivary gland tumors in Brazil. MATERIAL AND METHODS Hospital records of 124 patients with salivary gland tumors diagnosed from January 1993 to December 1999 were reviewed. The patients were analyzed according to gender, age, ...

Objectives This study aimed to assess PD-1gene polymorphism in salivary gland tumors in patients referred to Khalili Hospital in Shiraz. Methods This case-control study evaluated 48 patients with salivary gland tumors and 100 age- and sex-matched healthy controls. First, 5cc blood samples were obtained from patients and transferred to vials containing anti-coagulated EDTA. DNA was extracted, a...

Salivary, mammary and prostate glands are sex hormone-dependent organs sharing common aspects in structure, hormonal responsiveness and tumor histopathology. Salivary tumors (especially the malignant types) are not as frequent as mammary and prostate neoplasias. Hence, prognosis of some salivary tumors is not always efficient. Here, we review the oncology of salivary gland and its putative rela...

BACKGROUND The immunohistochemical detection of Enhancer of zeste homologue 2 (EZH2) proved to be a useful tool to recognize the malignant nature of tumors in a wide variety of neoplasms. The histological diagnostics of salivary gland tumors is a challenging task, and a reliable marker of malignancy would be extremely helpful. METHODS EZH2 expression was investigated in 54 malignant and 40 be...

INTRODUCTION Natural killer (NK) cells, of which CD56 is a specific marker, play an important role in host defense against tumors. Cancer stem cells, of which aldehyde dehydrogenase isoform 1 (ALDH1) is an immunohistochemical marker, are a group of tumorigenic cells which are involved in migration and tumor recurrences. We aimed to evaluate the expression of ALDH1 and CD56 in common salivary gl...